Salmonella enterica and outer membrane vesicles are current and future options for cancer treatment
Genesy Pérez Jorge,
Marco Túlio Pardini Gontijo,
Marcelo Brocchi
Abstract:Conventional cancer therapies have many limitations. In the last decade, it has been suggested that bacteria-mediated immunotherapy may circumvent the restrictions of traditional treatments. For example, Salmonella enterica is the most promising bacteria for treating cancer due to its intrinsic abilities, such as killing tumor cells, targeting, penetrating, and proliferating into the tumor. S. enterica has been genetically modified to ensure safety and increase its intrinsic antitumor efficacy. This bacterium … Show more
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