Salmonella Derby from pig production chain over a 10-year period: antimicrobial resistance, biofilm formation, and genetic relatedness

Simoni, Cintia; Ausani, Thais de Campos; Laviniki, Vanessa; Lopes, Graciela Völz; Cardoso, Marisa Ribeiro de Itapema

doi:10.1007/s42770-022-00846-7

Cited by 5 publications

(2 citation statements)

References 47 publications

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“…[ 1 ]. Moreover, a previous report indicated that most Salmonella derby strains have the ability to form a biofilm, and then were categorized as non-wildtype or resistant to tetracycline and streptomycin [ 22 ]. Therefore, in addition to drug control and physical prevention and control, it may be a long-term goal to find the resistance genes or pathways against Salmonella in host cells.…”

Section: Discussionmentioning

confidence: 99%

The Metabolic Pathway of Bile Secretion Is Vulnerable to Salmonella enterica Exposure in Porcine Intestinal Epithelial Cells

Cai,

Chen,

et al. 2024

Animals

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Pigs can be colonized with Salmonella enterica and become established carriers. However, the mechanisms of the host’s response to Salmonella enterica infection are largely unclear. This study was constructed with the Salmonella enterica infection model in vitro using porcine intestinal epithelial cells (IPEC-J2). Transcriptome profiling of IPEC-J2 cells was carried out to characterize the effect of Salmonella enterica infection and lipopolysaccharide (LPS) treatment, in which LPS-induced inflammation was a positive control. At first, Salmonella enterica infection increased the cell apoptosis rate and induced an inflammation response in IPEC-J2. Then, the up-regulated genes were enriched in metabolic pathways, such as those for bile secretion and mineral absorption, while down-regulated genes were enriched in immune-related pathways, such as the Toll-like receptor signaling and p53 signaling pathways. Moreover, we found 368 up-regulated genes and 101 down-regulated genes in common. Then, an integrative analysis of the transcriptomic profile under Salmonella enterica infection and LPS treatment was conducted, and eight up-regulated genes and one down-regulated gene were detected. Among them, AQP8 is one critical gene of the bile secretion pathway, and its mRNA and protein expression were increased significantly under Salmonella enterica infection and LPS treatment. Thus, the AQP8 gene and bile secretion pathway may be important in IPEC-J2 cells under Salmonella enterica infection or LPS treatment.

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Section: Discussionmentioning

confidence: 99%

The Metabolic Pathway of Bile Secretion Is Vulnerable to Salmonella enterica Exposure in Porcine Intestinal Epithelial Cells

Cai,

Chen,

et al. 2024

Animals

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“…In case of S. Derby isolates, relatively long persistence in the environments of pig farms as well as biofilm formation were confirmed. In addition, resistance to a wide range of antiobiotics with different mechanisms of action was found (Simoni et al 2022) as well as the ability to participate in the spread of antimicrobial resistance among animal species (Gonzalez-Santamarina et al 2021). The monophasic S. Typhimurium serovar has been on the rise in the pig population in recent years and it is gradually replacing S. Typhimurium serovars (Bonardi et al 2016;Cota et al 2019).…”

Section: Discussionmentioning

confidence: 99%

Occurrence of Salmonella spp. in fattening pigs at a slaughterhouse in the Czech Republic

Veselá,

Dušková,

Furmančíková

et al. 2024

Acta Vet. Brno

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The aim of this study was to evaluate the occurrence of Salmonella spp. in fattening pigs in a slaughterhouse in the Czech Republic. Tonsils, mesenteric lymph nodes, and caecal contents were sampled from 120 pigs originating from eight farms. A total of 360 samples were examined. Cultivation methods were used to detect Salmonella. Suspect isolates were subjected to phenotypic identification. Serotyping was performed by slide agglutination method. The multiplex polymerase chain reaction (PCR) was used to detect genes encoding flagellar proteins. Salmonella spp. was isolated in 3 out of 360 samples (0.83%). The results proved the presence of serovars S. Typhimurium, S. Derby, and monophasic S. Typhimurium. Although our study found a relatively low prevalence of Salmonella in fattening pigs at the Czech slaughterhouse, consistent implementation of Salmonella control program during pork production is critical in order to ensure the protection of consumer health.

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Pan-Genome-Wide Association Study reveals a key role of the salmochelin receptor IroN in the biofilm formation of Salmonella Typhimurium and its monophasic variant 4,[5],12:i:-

Arrieta-Gisasola,

Martínez-Ballesteros,

Martinez-Malaxetxebarria

et al. 2024

International Journal of Food Microbiology

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Salmonella Derby from pig production chain over a 10-year period: antimicrobial resistance, biofilm formation, and genetic relatedness

Cited by 5 publications

References 47 publications

The Metabolic Pathway of Bile Secretion Is Vulnerable to Salmonella enterica Exposure in Porcine Intestinal Epithelial Cells

The Metabolic Pathway of Bile Secretion Is Vulnerable to Salmonella enterica Exposure in Porcine Intestinal Epithelial Cells

Occurrence of Salmonella spp. in fattening pigs at a slaughterhouse in the Czech Republic

Pan-Genome-Wide Association Study reveals a key role of the salmochelin receptor IroN in the biofilm formation of Salmonella Typhimurium and its monophasic variant 4,[5],12:i:-

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