Salivary Gland Neoplasms With a Unique Trabecular Histology and MAML2 Translocation
Bokyung Ahn,
Seung-Ho Choi,
Doeun Kim
et al.
Abstract:Mucoepidermoid carcinomas (MECs) are the most common salivary gland malignancy and have a diverse histology. Many histologic variants of MEC have now been confirmed with characteristic molecular alterations involving CRTC1::MAML2 or CRTC1::MAML3 translocations. We here report a series of 7 trabecular variants of MEC which showed a predominant trabecular or nested pattern with either focal glandular differentiation or clear cell change and keloid-like fibrosis in the background. In addition, these tumors were e… Show more
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