Salivary gland malignancies in children

Yoshida, Emi; García, Joaquín J.; Eisele, David W.; Chen, Allen M.

doi:10.1016/j.ijporl.2013.11.001

Cited by 58 publications

(87 citation statements)

References 38 publications

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“…Superficial or lateral parotidectomy for a laterally located tumour mass is the typical procedure. Total parotidectomy may be required for deep lobe or parapharyngeal tumour mass lesions [27] or when the tumour mass is suspected or confirmed to be high grade or to have aggressive malignant potential, such as a mass presenting with a facial nerve palsy, multiple intraparotid masses, or a mass coupled with the presence of cervical metastasis [2,5,6,16,20,[31][32][33] . Resection of the facial nerve is currently recommended when there is gross anatomic or histological evidence of nerve invasion at the time of surgery.…”

Section: Parotid Glandmentioning

confidence: 99%

“…Resection of the facial nerve is currently recommended when there is gross anatomic or histological evidence of nerve invasion at the time of surgery. Should the nerve trunk, nerve division or a named branch be resected, immediate nerve repair by means of a primary anastomosis or a free nerve graft is advocated [2,33] .…”

Section: Parotid Glandmentioning

confidence: 99%

“…The majority (>95%) are epithelial, with a minor group being mesenchymal in origin. When a solitary SGN is present, the chance of malignancy is greater in a child than in an adult [1][2][3] . The concept that paediatric SGNs are more likely malignant than adult SGNs has been challenged by suggestions that previous data have been 'selected material' and by reporting of a nationwide survey from Denmark over a 16-year period (1990-2005) [4] .…”

Section: Introductionmentioning

confidence: 99%

“…The parotid gland is involved in >85% of all reported paediatric SGNs [1][2][3][4] . Minor SGNs do occur, with the majority located in the oral cavity; other sites have also been reported, usually as case reports, including the pharynx, larynx and bronchus [5] .…”

Section: Introductionmentioning

confidence: 99%

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Salivary Gland Neoplasms in Children and Adolescents

Bradley

Eisele

2016

Salivary Gland Neoplasms

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Salivary gland neoplasms (SGNs) in children are uncommon. Epithelial SGNs (ESGNs) comprise the majority (95%), with the remaining being mesenchymal SGNs (MeSGNs). Pleomorphic adenoma is the most frequently encountered benign neoplasm, mucoepidermoid carcinoma is the most frequent malignant ESGN, and rhabdomyosarcoma is the most frequent malignant MeSGN. ESGN presents in the second decade, whereas MeSGN presents in the first and second decades. Swelling without pain or neurological signs is the main presentation of both benign and malignant neoplasms. Making an accurate preoperative histological diagnosis is important, so a needle biopsy or a perioperative frozen section is useful when there is doubt about the disease status of the patient; the excised tumour margin is also important. Surgical excision should aim to achieve clear margin excision in benign and malignant ESGNs, minimising the need for adjuvant radiotherapy and maximising the long-term likelihood of patient cure. Benign ESGNs are uncommon, and excision is curative, whereas malignant ESGN and MeSGN should be managed by a multidisciplinary paediatric oncology team.

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Section: Parotid Glandmentioning

confidence: 99%

Section: Parotid Glandmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Salivary Gland Neoplasms in Children and Adolescents

Bradley

Eisele

2016

Salivary Gland Neoplasms

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“…MEC is considered as the most common primary salivary gland malignancy and patients have a mean age of 45 years old at the time of diagnosis [49,50]. Children are rarely involved and gender diferences are not marked [51,52].…”

Section: Mucoepidermoid Carcinomamentioning

confidence: 99%

Salivary Gland Cancers: A Survey through History, Classifications and Managements

Khosravi¹,

Bagherihagh²,

Saeedi³

et al. 2017

Diagnosis and Management of Head and Neck Cancer

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In this chapter, we are going to discuss about salivary glands cancers, their clinical manifestations and categories, pathogenesis, diagnosis and treatment. We will go through details in each part in both clinical and surgical aspects based on recently prominent published studies and research in prestigious journals. After a short review on clinical features, epidemiology, pathogenesis, diagnosis and treatment, we will show staging and tumor node metastasis (TNM) classiication of major salivary gland tumors and also basic principles of approach to salivary gland cancers. A litle will be explained about basic surgical procedures for removal of cancers and benign tumors.

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Pediatric Salivary Gland Pathology

Carlson

Ord

2015

Salivary Gland Pathology

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Salivary gland malignancies in children

Cited by 58 publications

References 38 publications

Salivary Gland Neoplasms in Children and Adolescents

Salivary Gland Neoplasms in Children and Adolescents

Salivary Gland Cancers: A Survey through History, Classifications and Managements

Pediatric Salivary Gland Pathology

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