Salivary Cortisol Levels and Burning Symptoms in Patients with Burning Mouth Syndrome before and after Low Level Laser Therapy: a Double Blind Controlled Randomized Clinical Trial

Škrinjar, Ivana; Brzak, Božana Lončar; Vidranski, Valentina; Boras, Vanja Vučičević; Rogulj, Ana Andabak; Pavelić, Božidar

doi:10.15644/asc54/1/5

Cited by 13 publications

(29 citation statements)

References 32 publications

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“…The studies were published between 2015 and 2020 and carried out in Spain ( 13 , 19 , 20 ), Brazil ( 12 , 14 ), Italy ( 21 ), Croatia ( 22 ) and Iran ( 11 ). The sources of information on the demographic and clinical characteristics of the population are available in Table 1 .…”

Section: Resultsmentioning

confidence: 99%

“…Two studies suggested the need for further research with established protocols and larger samples to determine the real effectiveness of laser therapy in BMS ( 21 , 22 ). Pedro et al .…”

Section: Resultsmentioning

confidence: 99%

“…All irradiated areas where the participants reported the symptoms of pain and burning sensation. Four studies did not report the exact locations of application ( 12 , 14 , 21 , 22 ). Two studies ( 13 , 14 ) reported that the application was on the oral mucosa, without describing the locations.…”

Section: Resultsmentioning

confidence: 99%

“…Instead, they showed time irradiated by point. One of the two studies that reported the total time exceeded the recommended: they radiated for 381 seconds ( 22 ). One area should not be irradiated for more than five minutes and the total treatment time (including all areas) should not exceed twenty minutes ( 9 ).…”

Section: Discussionmentioning

confidence: 99%

“…Seven studies in the sample reported outcomes that point to the effectiveness of low-level laser therapy, with reduced pain and burning sensation in the treated participants; three of them demonstrated statistical significance between the groups ( 12 , 19 , 22 ).…”

Section: Discussionmentioning

confidence: 99%

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Efficacy of the laser at low intensity on primary burning oral syndrome: a systematic review

Matos

Silva²,

Paranhos³

et al. 2021

Med Oral

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Background Primary burning mouth syndrome (BMS) is a chronic clinical condition of idiopathic mainly characterized by pain and a burning sensation in the oral cavity. The application of laser at low intensity therapy is a treatment option. This systematic review evaluated the efficacy of laser therapy in treating symptoms of burning mouth syndrome. Material and Methods The study was formulated according to the PRISMA and Cochrane guidelines. Seven databases were used as primary sources of research. Only randomized controlled clinical trials were included. The efficacy of the therapy was estimated comparing the values of the visual and numerical scales of pain before and after laser treatment, through qualitative analysis. Results The search resulted in 348 records and only eight filled the eligibility criteria and were included. All studies evaluated pain and / or a burning sensation considering a time interval of two to ten weeks. The total sample consisted of 314 patients submitted to treatment: 123 from the control group, who participated with laser off or with the tip blocked, and 191 from the intervention group, treated with low-level laser therapy. The female gender stood out and the average age of the participants was 60.89 years. The main symptoms reported were pain and a burning sensation in the oral mucosa and tongue. The parameters adopted by the authors for laser treatment were diverse and the variables were not fully described in the published studies. Visual analog and numerical scales were used to assess symptoms and only three studies showed statistical significance. Conclusions It is suggested that laser therapy may be an effective alternative in the treatment of BMS. New randomized clinical trials should consider well-established protocols to better understand the efficacy of laser therapy without confounding the effects. Key words: Efficacy, systematic review, burning mouth syndrome, low level laser therapy.

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Section: Resultsmentioning

confidence: 99%

“…Two studies suggested the need for further research with established protocols and larger samples to determine the real effectiveness of laser therapy in BMS ( 21 , 22 ). Pedro et al .…”

Section: Resultsmentioning

confidence: 99%