Salivary and hair cortisol as biomarkers of emotional and behavioral symptoms in 6–9 year old children

Golub, Yulia; Kuitunen‐Paul, Sören; Panaseth, Kerstin; Stonawski, Valeska; Frey, Stefan; Steigleder, Ruth; Grimm, Jennifer; Goecke, Tamme W.; Fasching, Peter A.; Beckmann, Matthias W.; Kornhuber, Johannes; Kratz, Oliver; Heinrich, Hartmut; Moll, Gunter H.; Eichler, Anna

doi:10.1016/j.physbeh.2019.112584

Cited by 18 publications

(14 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This means that this group of children deserves extra attention in schools: how can we support these children to regulate their inhibitory control (for specific tasks) and how can we adapt the school environment to support these children? Several interventions use self-regulation techniques such as relaxation, yoga, and imagery to effectively improve wellbeing, health-related issues, and cognitive or emotional control in children (Bell & Deater-Deckard, 2007;Bothe et al, 2014;Ehud, An, & Avshalom, 2010;Goldbeck & Schmid, 2003;Lee & Olness, 1996). The Bothe et al, (2014) intervention with the 10-min daily stress management technique also included these self-regulation techniques.…”

Section: Discussionmentioning

confidence: 99%

“…Although researchers have used HCC widely to approximate stress levels in adults (Sauve, Koren, Walsh, Tokmakejian, & Van Uum, 2007;Stalder et al, 2017;Stalder & Kirschbaum, 2012;Staufenbiel, Penninx, Spijker, Elzinga, & Van Rossum, 2013), this measure is less often used in early childhood (Bates et al, 2017;Golub, Kuitunen-Paul, & Panaseth, 2019;Gray et al, 2018). The studies that measured HCC in children especially focused on chronic stress, not on stress during transitions (Yamada et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

“…Although stress responses are necessary for survival, chronic exposure to stress can change from adaptive to maladaptive (De Kloet, Oitzl, & Jo€ els, 1999;Segerstrom & Miller, 2004). Previous studies have shown that higher stress levels in children are related to behavior changes, anxiety, sleep problems, illness, and cognitive functioning (B€ aumler et al, 2014;Forbes et al, 2005;Golub et al, 2019;Kenny, Gallagher, Alvarez-Salvat, & Silsby, 2002;Lipton, Becker, & Kothare, 2008;Turner Cobb & Steptoe, 1998;Windle & Windle, 1996).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Children’s hair cortisol as a biomarker of stress at school: a follow-up study

Groeneveld

Savas

Rossum

et al. 2020

Stress

View full text Add to dashboard Cite

In a previous study, we examined hair cortisol concentrations (HCCs) in children when first entering elementary school (at 4 years). In this follow-up study, we examined their HCC when they entered third grade (at 6 years), where the more playful first grades proceed into a more formal learning setting. Participants were 30 6-year-old children (14 boys). Hair samples (!5 cm) were collected 2 months after the summer holidays. Hair analysis was conducted using two 2-cm long segments, reflecting the first 2 months of school attendance in grade 3 (the scalp-near segment), and 2 months prior to the start in grade 3. Between these two sections, we left a gap of 1 cm to avoid overlap of periods (due to differences in hair growth rate). Children showed a significant increase in cortisol levels when they entered third grade. This increase was not associated with social fearfulness or academic achievement, but did show significant associations with inhibitory control: children with less inhibitory control had higher cortisol levels after entering third grade, and larger increases in cortisol than children with higher scores on inhibitory control. This suggests that the ability to inhibit or control impulsive responsivity is important for children's stress regulation when making the transition to a more formal school environment.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Children’s hair cortisol as a biomarker of stress at school: a follow-up study

Groeneveld

Savas

Rossum

et al. 2020

Stress

View full text Add to dashboard Cite

show abstract

“…Finally, as many children and adolescents with TDs are affected by comorbid emotional and behavioral problems [24,27] and take psychotropic medication for symptom reduction of tics [28], we were interested in their potential main and interaction effects on HCC. Based on findings for associations of saliva and hair cortisol with emotional and behavior problems [22,[29][30][31], we assumed lower HCC levels in children with TD and a high level of comorbid conduct problems compared to children with TD but no conduct problems. For children with TD and a high level of emotional problem scores, we assumed higher HCC levels compared to children with TD without emotional problems.…”

Section: Introductionmentioning

confidence: 99%

Hair cortisol-a stress marker in children and adolescents with chronic tic disorders? A large European cross-sectional study

Buse

Rothe

Uhlmann

et al. 2021

Eur Child Adolesc Psychiatry

View full text Add to dashboard Cite

Background There is clear evidence that tic disorders (TDs) are associated with psychosocial stress as well as emotional and behavioral problems. Studies have shown that individuals with TDs have higher acute physiological stress responses to external, single stressors (as reflected by saliva cortisol). The aim of the present study was to examine a physiological marker of longer-term stress (as reflected by hair cortisol concentration) in children and adolescents with TDs and unaffected siblings of individuals with TDs. Methods Two samples of a European cohort were included in this study. In the COURSE sample, 412 children and adolescents aged 3–16 years with a chronic TD including Tourette syndrome according to DSM IV-TR criteria were included. The ONSET sample included 131 3–10 years old siblings of individuals with TDs, who themselves had no tics. Differences in hair cortisol concentration (HCC) between the two samples were examined. Within the COURSE sample, relations of HCC with tic severity and perceived psychosocial stress as well as potential effects and interaction effects of comorbid emotional and behavioral problems and psychotropic medication on HCC were investigated. Results There were no differences in HCC between the two samples. In participants with TDs, there were no associations between HCC and tic severity or perceived psychosocial stress. No main effects of sex, psychotropic medication status and comorbid emotional and behavioral problems on HCC were found in participants with TDs. Conclusion A link between HCC and TDs is not supported by the present results.

show abstract

“…In adults, studies show positive (Pulopulos et al., 2014), negative (Assayag et al., 2017), and null (McLennan et al., 2016) associations between HCC and cognitive functioning. In children, HCC is associated with related constructs; higher HCC predicts fewer ADHD symptoms (Pauli‐Pott et al., 2019; Schloß et al., 2018) but also more behavior problems (Golub et al., 2019). A recent study of Pakistani preschoolers found a negative association between HCC and cognitive skills including EF, but only for girls with higher family wealth (Armstrong‐Carter et al., 2020).…”

Section: Introductionmentioning

confidence: 99%

Lifetime stressors, hair cortisol, and executive function: Age‐related associations in childhood

DePasquale

Tyrell

Kalstabakken

et al. 2020

Developmental Psychobiology

View full text Add to dashboard Cite

Extant research is mixed regarding the relations among lifetime exposure to stressors, adrenocortical activity, and executive function (EF), particularly in children. Aggregate measures of adrenocortical activity like hair cortisol concentration (HCC), timing of stress exposure, and age at assessment may clarify these associations. This cross‐sectional study examined the association among parent‐reported exposure to stressors, hair cortisol concentration (HCC), and children's EF via a tablet task in a community sample (n = 318, 52.5% female) of children across a wide age range (4–13 years, M = 9.4, SD = 2.3). Path analyses revealed that parent‐reported child lifetime exposure to stressors, but not past‐year stressful life events, negatively predicted HCC. There was also a marginally significant moderation by age such that HCC was associated negatively with EF for younger children (age < 9.7 years) but not older children. HCC did not significantly mediate the association between lifetime exposure to stressors and EF. Findings are consistent with the proposition that chronically high cortisol production has a neurotoxic effect on brain regions supporting EF. However, lifetime exposure to stressors predicted relatively lower cumulative cortisol production, consistent with a stress inoculation effect in this normative‐risk sample.

show abstract

Salivary and hair cortisol as biomarkers of emotional and behavioral symptoms in 6–9 year old children

Cited by 18 publications

References 52 publications

Children’s hair cortisol as a biomarker of stress at school: a follow-up study

Children’s hair cortisol as a biomarker of stress at school: a follow-up study

Hair cortisol-a stress marker in children and adolescents with chronic tic disorders? A large European cross-sectional study

Lifetime stressors, hair cortisol, and executive function: Age‐related associations in childhood

Contact Info

Product

Resources

About

Salivary and hair cortisol as biomarkers of emotional and behavioral symptoms in 6–9 year old children

Cited by 18 publications

References 52 publications

Children’s hair cortisol as a biomarker of stress at school: a follow-up study

Children’s hair cortisol as a biomarker of stress at school: a follow-up study

Hair cortisol-a stress marker in children and adolescents with chronic tic disorders? A large European cross-sectional study

Lifetime stressors, hair cortisol, and executive function: Age‐related associations in childhood

Contact Info

Product

Resources

About

Salivary and hair cortisol as biomarkers of emotional and behavioral symptoms in 6–9 year old children