Saliva Leptin Levels in Tooth Movement during Initial Stage of Orthodontic Alignment: A Pilot Study

Bakar, Noraini Abu; Kamil, Wisam Alaa; Bayati, Lina Al; Mustafa, Basma Ezzat

doi:10.20396/bjos.v16i0.8651060

Cited by 2 publications

(3 citation statements)

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“…Saliva was collected at the same time (8 a.m.) for all patients to eliminate differences in circadian rhythmicity as done in several previous studies. 11 19 20 Samples were then centrifuged at 4,000× g ; 10 minutes and stored at–25°C.…”

Section: Methodsmentioning

confidence: 99%

“…With regards to leptin in orthodontics, a preliminary study done by Bakar et al, 11 concluded that leptin concentration in saliva is decreased during orthodontic tooth movement in initial alignment stage and that leptin may be one of the mediators associated with orthodontic tooth movement.…”

Section: Introductionmentioning

confidence: 99%

“…There have been studies that have looked into the leptin hormone and how it affects orthodontic tooth movement. 11 It would be useful to know if this hormone differs in various classes of facial skeletal pattern prior to orthodontic treatment and we aim to address that in this prefatory study.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of Salivary Leptin Levels and Its Correlation with Class I, Class II, and Class III Facial Skeletal Pattern: A Prefatory Study

2021

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Materials and Methods A sample of 62 patients were selected prior to the orthodontic treatment from a population that attended the International Islamic University Malaysia Specialist Orthodontic Clinic. Based on the lateral cephalometric analysis, the subjects were grouped into Class I, Class II, and Class III facial skeletal patterns, according to Eastman and Wits appraisal. Subsequently, unstimulated saliva samples were taken and purified to undergo leptin enzyme-linked immunosorbent assay analysis to determine the levels of leptin hormone. Statistical analysis using the Kruskal–Wallis test was used to analyze the data obtained. Results The results showed that there was a significant difference between the levels of leptin hormone between Class I and Class II skeletal patterns and between Class I and Class III facial skeletal patterns. No statistical difference was noted between the levels of leptin of Class II and Class III facial skeletal patterns. Conclusion Salivary leptin hormone levels are higher in patients with Class II and Class III facial skeletal patterns compared with Class I.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%