“…Because it is thought that 2,6-dichloroisonicotinic acid acts at the same point as or downstream of SA in this pathway (Delaney et al, 1995), one conclusion is that these mutants define steps in a feedback loop operating to interpret SA-dependent signals. These genetic results are consistent with other results implicating a feedback role for SA during the defense response (Kauss et al, 1992;Kauss and Jeblick, 1995;Mauch-Mani and Slusarenko, 1996;Mur et al, 1996; see also Ryals et al, 1996, in this issue). It will also be informative to combine the cell death control mutants with other mutants required for R gene function, such as ndr (Century et al, 1995), whose position in the scheme shown in Figure 2 is tentative.…”