Salicylic Acid Peel Incorporating Triethyl Citrate and Ethyl Linoleate in the Treatment of Moderate Acne: A New Therapeutic Approach

Raone, Beatrice; Veraldi, Stefano; Raboni, Roberta; Ardigò, Marco; Patrizi, Annalisa; Micali, Giuseppe

doi:10.1111/dsu.12215

Cited by 3 publications

(2 citation statements)

References 14 publications

(43 reference statements)

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“…Furthermore, authors conclude that the efficacy of this lotion was based on the ability of linoleic acid in reducing the inflammation mediated by the neutrophils and the 5a‐reductase activity. In fact it has been demonstrated that linoleic acid downregulates neutrophilic oxygen metabolism and phagocytosis (Raone et al, ).…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, authors conclude that the efficacy of this lotion was based on the ability of linoleic acid in reducing the inflammation mediated by the neutrophils and the 5a-reductase activity. In fact it has been demonstrated that linoleic acid downregulates neutrophilic oxygen metabolism and phagocytosis (Raone et al, 2013). Use of this lotion containing triethyl citrate and ethyl linoleate could reduce the risk of antibiotic resistance also because HS is not a «classic» infectious disease: there is no unique bacterial agent but a polymorphic flora (Al-Hamamy, NoaimiI, Al-Turfy, & Rajab, 2015).…”

Section: Discussionmentioning

confidence: 99%

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Efficacy and tolerability of a lotion containing triethyl citrate, ethyl linoleate, and GT peptide-10 in the adjuvant treatment of hidradenitis suppurativa: Real-life data

Skroza

Mambrin

Tolino

et al. 2018

Dermatologic Therapy

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Hidradenitis suppurativa (HS) is a chronic disorder of terminal follicular epithelium in the apocrine gland-bearing areas. The long term therapy is based mainly on topical and/or systemic antibiotic use that could result in antibiotic resistance. The aim of our study was to present the real-life experience based on the efficacy and tolerability of a novel lotion containing triethyl-citrate, ethyl-linoleate, and g-peptide-10 in the treatment of mild to moderate HS that has already shown effectiveness in acne treatment. This was an open-label study on 30 patients of both sexes affected by HS. Patients were divided into two groups: 15 with Hurley I and 15 with Hurley II-III. The subjects were treated with the topical lotion, three-times-daily for eight weeks, with control at 4 (T ) and eight weeks (T ). Any other concomitant treatment (both topical and/or systemic) was avoided during study period. Improvement was observed in both Sartorius score grading system and inflammatory and noninflammatory lesion counts. The novel lotion has proved to be effective and well-tolerated topical agent alone or in association with other topical and/or systemic tratments in HS, without side effects.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%