Sales of systemic anti-infective agents in Cyprus in comparison with four other European countries

Hadjimichael, Christos; Georgiou, Kyriacos; Samoutis, George; Demetriades, Evros

doi:10.1007/s11096-006-9006-x

Cited by 5 publications

(3 citation statements)

References 9 publications

(14 reference statements)

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“…The actual defined daily doses (DDDs) of antimicrobials were not known per se during this study. However, earlier sale trends of systemic anti-infective agents in Cyprus revealed that there was one of the highest values in comparison with other European countries ( Hadjimichael et al, 2006 ; ESAC, 2009 ). Another independent cross-sectional study showed that 97,6% of community pharmacists in the north of Cyprus engaged in inappropriate antimicrobial dispensing without medical prescriptions (Kaya Suer et al, 2015, unpublished survey).…”

Section: Resultsmentioning

confidence: 94%

High Emergence of ESBL-Producing E. coli Cystitis: Time to Get Smarter in Cyprus

et al. 2016

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Background: Widespread prevalence of extended-spectrum βeta-lactamase producing Escherichia coli (ESBL-producing E. coli) limits the infection therapeutic options and is a growing global health problem. In this study our aim was to investigate the antimicrobial resistance profile of the E. coli in hospitalized and out-patients in Cyprus.Results: During the period 2010–2014, 389 strains of E. coli were isolated from urine samples of hospitalized and out-patients in Cyprus. ESBL-producing E. coli, was observed in 53% of hospitalized and 44% in out-patients, latest one being in 2014. All ESBL-producing E. coli remained susceptible to amikacin, carbapenems except ertapenem (in-patients = 6%, out-patients = 11%).Conclusion: High emerging ESBL-producing E. coli from urine samples in hospitalized and out-patients is an extremely worrisome sign of development of untreatable infections in the near future on the island. We therefore emphasize the immediate need for establishment of optimal therapy guidelines based on the country specific surveillance programs. The need for new treatment strategies, urgent prescription habit changes and ban of over-the-counter sale of antimicrobials at each segment of healthcare services is also discussed in this research.

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Section: Resultsmentioning

confidence: 94%

High Emergence of ESBL-Producing E. coli Cystitis: Time to Get Smarter in Cyprus

et al. 2016

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“…An increase in quantity sales of these medicines in several European countries during 1990-1996 was reported (Hadjimichael et al 2006). In Thailand, though there was no similar report, the expenditure on such medicines accounted for about 23.5%, which was the highest portion of the total in 1999 (Wibulpolprasert 2002).…”

Section: Introductionmentioning

confidence: 95%

Factors associated with the market availability of systemic anti-infective products in Thailand (no. 743)

et al. 2009

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Background Despite the fact that the market availability of medicines has been recognized as one of the most important components in the health-care system, its association with other factors is still in doubt. Objective This study aimed at determining the factors associated with the number of trade names and products of systemic anti-infective medicines available for the market in Thailand. Methods A cross-sectional study on the data from the Thai National List of Essential Medicines (Thai EML) 2008 and Thailand Index of Medical Specialties 2008 was undertaken.Results Results showed a total of 702 trade names and 1,262 products from 137 generic drugs. Half of the products belonged to the classes of beta-lactam antibacterials (39%) and quinolone antibacterials (11.3%). The significant factors found were dosage forms of medicines, manufacturer types and category. The generic drugs that were prepared in more than one dosage form, produced by local manufacturers and categorized as essential medicines (EMs) would have a greater number of trade names and products than those done in one dosage form by foreign manufacturers and as non-EMs. Conclusion There are at least three factors associated with the number of trade names and products of systemic antiinfective medicines, which include dosage forms of medicines, manufacturer types and EM category. These factors have involved the technical issue, private sector and Thai EML. One suggestion from this finding is to use the Thai EML as a means to control the market availability of systemic anti-infective products in the country.

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“…Our indicator data for environmental stressors were derived from historical observations from different public recordings and may contain observational bias. Some of the unique exposure levels were, however, supported by the literature; for example, severe exposure to antibiotics in Cyprus primarily arises from the high consumption of anti-infective agents 31 .…”

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confidence: 99%

Vulnerability of blue foods to human-induced environmental change

Cao,

Halpern,

Troell

et al. 2023

Nat Sustain

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Global aquatic or ‘blue’ foods, essential to over 3.2 billion people, face challenges of maintaining supply in a changing environment while adhering to safety and sustainability standards. Despite the growing concerns over their environmental impacts, limited attention has been paid to how blue food production is influenced by anthropogenic environmental changes. Here we assess the vulnerability of global blue food systems to predominant environmental disturbances and predict the spatial impacts. Over 90% of global blue food production faces substantial risks from environmental change, with the major producers in Asia and the United States facing the greatest threats. Capture fisheries generally demonstrate higher vulnerability than aquaculture in marine environments, while the opposite is true in freshwater environments. While threats to production quantity are widespread across marine and inland systems, food safety risks are concentrated within a few countries. Identifying and supporting mitigation and adaptation measures in response to environmental stressors is particularly important in developing countries in Asia, Latin America and Africa where risks are high and national response capacities are low. These findings lay groundwork for future work to map environmental threats and opportunities, aiding strategic planning and policy development for resilient and sustainable blue food production under changing conditions.

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Sales of systemic anti-infective agents in Cyprus in comparison with four other European countries

Cited by 5 publications

References 9 publications

High Emergence of ESBL-Producing E. coli Cystitis: Time to Get Smarter in Cyprus

High Emergence of ESBL-Producing E. coli Cystitis: Time to Get Smarter in Cyprus

Factors associated with the market availability of systemic anti-infective products in Thailand (no. 743)

Vulnerability of blue foods to human-induced environmental change

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