Salbutamol premedication in children with a recent respiratory tract infection

Ungern‐Sternberg, Britta S. von; Habre, Walid; Erb, Thomas O.; Heaney, Mairead

doi:10.1111/j.1460-9592.2009.03130.x

Cited by 74 publications

(50 citation statements)

References 33 publications

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“…The incidence of perioperative laryngospasm varies widely in the literature from 0.1 to 16 %, primarily due to differences in its definition [20,39]. While perioperative laryngospasm occurs in approximately 4 % of children in a general pediatric population [8,13], smaller frequencies have been reported in retrospective studies or when only severe forms have been reported (e.g., laryngospasm triggering a ''call for help'') [1, 2 • , 17, 39, 40, 41 •• ], whereas greater frequencies have been reported in children with associated risk factors (Table 1).…”

Section: Laryngospasm Epidemiologymentioning

confidence: 98%

“…Premedication Premedication with beta-2 agonists is recommended for all children with moderate or severe asthma or in those who are actively wheezing due to reactive airway disease (e.g., upper respiratory tract infection) in order to reduce the risk of PRAE [20,82,83].…”

Section: Bronchospasm Preventionmentioning

confidence: 99%

“…Preoperative salbutamol either via metered dose inhaler or via nebulizer (2.5 mg if weight\20 kg, 5 mg if weight[20 kg) 10-30 min prior to surgery may reduce the risk of laryngospasm and bronchospasm in patients with recent upper respiratory tract infection [20].…”

Section: Other Agentsmentioning

confidence: 99%

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Diagnosis and Management of Respiratory Adverse Events in the Operating Room

Regli

Ungern‐Sternberg

2015

Curr Anesthesiol Rep

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Perioperative respiratory adverse events cause more than three-quarters of all perioperative critical incidents in pediatric anesthesia and approximately half of anesthesia-related cardiac arrests. We can define seven main clinical types of perioperative respiratory adverse events: upper airway obstruction, laryngospasm, bronchospasm, severe persistent cough, apnea, stridor, and oxygen desaturation. Depending on the definitions used for preoperative respiratory adverse events and the cohort of children examined, the incidence varies between 8 and 21 %. This review discusses the recognition and treatment of perioperative respiratory adverse events. Furthermore, it provides guidance on how to identify children who are at increased risk for developing perioperative respiratory adverse events and how to tailor the perioperative anesthetic management for the individual child in order to minimize the risk of perioperative respiratory adverse events.

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Section: Laryngospasm Epidemiologymentioning

confidence: 98%

Section: Bronchospasm Preventionmentioning

confidence: 99%

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Diagnosis and Management of Respiratory Adverse Events in the Operating Room

Regli

Ungern‐Sternberg

2015

Curr Anesthesiol Rep

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“…Previous studies suggested that laryngospasm was always occurred due to the increase of respiratory secretions, the mechanical irritations of endotracheal tube and the effects of anesthetic drugs, as well as the upper respiratory tract infections/potential infection and the suppression of mucociliary clearance by dry airflow during ventilation [6][7][8]. The occurrence of laryngospasm could bring rapid deterioration in systemic oxygenation and cyanosis, and decrease in surplus pulse O 2 (SpO 2 ), even become lifethreatening if some interventions were delayed [8,9].…”

Section: Introductionmentioning

confidence: 99%

The effect of premedication with budesonide aerosol inhalation on the incidence of respiratory adverse events during anesthesia recovery period in pediatric patients

Huang¹,

Yang²,

Jiang³

2018

biomedicalresearch

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Objective: We aimed to investigate the influence of premedication with budesonide aerosol inhalation on the incidence of respiratory adverse events during anesthesia recovery period in pediatric patients. Method: 120 pediatric patients underwent elective surgery of inguinal hernia repair were enrolled in the study. They were given two different types of anesthesia, group A received general anesthesia with the Laryngeal Mask (LMA), and group B were treated with budesonide aerosol inhalation preoperatively before general anesthesia with LMA. The incidence of adverse events which included laryngospasm, respiratory tract infection, the length of Post-Anesthesia Care Unit (PACU) staying, the volume of throat secretions and hoarseness were monitored closely. Results: Compared with group A, group B had a lower incidence of respiratory adverse events. Conclusion: Preoperative budesonide aerosol inhalation could reduce the incidence of respiratory adverse events during the anesthesia recovery period in children.

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“…Additional short acting β-agonists are indicated regardless of disease level, as benefits counteracting the bronchial constrictive response to tracheal intubation have been demonstrated [29,[43][44][45][46][47]. Preoperative anxiolytics such as midazolam assist in mitigating anxiety-induced bronchospasm [48].…”

Section: Preoperative Managementmentioning

confidence: 99%

The Perioperative Management of Asthma

Applegate

2013

J Allergy Ther

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Anesthesiologists encounter asthmatic patients routinely. This common disease frequently complicates the perioperative care of those patients who live with it and can occasionally lead to life-threatening complications. This review takes the anesthesiologist's perspective to discuss asthma and how asthmatic patients can be safely guided through an anesthetic. We will discuss frequently used asthma medications, pre-operative disease optimization, management of intra-operative bronchospasm, and post-operative considerations for asthmatic patients. Anesthesiologists can make a positive difference in the outcomes of these patients with proper preoperative evaluation using a stepwise approach to disease management and by minimizing bronchoconstriction and effectively treating it when it develops.

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Salbutamol premedication in children with a recent respiratory tract infection

Abstract: The results from this audit suggest that children with a history of a recent RTI have significantly less PRAE following a premedication with salbutamol compared with no premedication. Therefore, premedication with salbutamol might be considered in children with recent RTI.

Cited by 74 publications

References 33 publications

Diagnosis and Management of Respiratory Adverse Events in the Operating Room

Diagnosis and Management of Respiratory Adverse Events in the Operating Room

The effect of premedication with budesonide aerosol inhalation on the incidence of respiratory adverse events during anesthesia recovery period in pediatric patients

The Perioperative Management of Asthma

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