Sagittal abdominal diameter is more predictive of cardiovascular risk than abdominal fat compartments in severe obesity

Guzzaloni, G; Minocci, Alessandro; Marzullo, Paolo; Liuzzi, Antonio

doi:10.1038/ijo.2008.271

Cited by 20 publications

(19 citation statements)

References 37 publications

(54 reference statements)

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“…With the exception of HOMA-IR, these associations were not elicited with WHR. Furthermore, in terms of identifying adult patients with MetS, SAD, in the absence of imaging techniques, has a sensitivity of 91% and specificity of 80% in patients at risk for cardiovascular events [24], and even more superior in assessing cardiovascular risk among the severely obese [25]. It is noted however that the predictive utility of SAD among normal adults, and in this case, children, will be clearly less as compared to those who harbor known CVD risk factors such as obesity.…”

Section: Discussionmentioning

confidence: 99%

Association of body mass index, sagittal abdominal diameter and waist-hip ratio with cardiometabolic risk factors and adipocytokines in Arab children and adolescents

et al. 2012

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BackgroundSagittal abdominal diameter (SAD) is a novel anthropometric measure hypothesized to be a surrogate measure of visceral abdominal obesity in adults. This study aims to determine whether SAD is superior to other anthropometric measures such as body mass index (BMI) and waist to hip ratio (WHR) in terms of association to cardiometabolic risk and circulating adipocytokine concentrations in a cohort of Saudi children and adolescents.MethodsA total of 948 (495 boys and 453 girls) apparently healthy children with varying BMI, aged 10–17 years, were included in this cross sectional study. Fasting glucose, lipid profile, leptin, adiponectin, resistin, insulin, TNF-α and aPAI-1 were measured in serum and HOMA-IR was calculated. MetS components were defined according to the International Diabetes Federation (IDF) criteria.ResultsBMI was superior to SAD as well as WHR, and had the highest number of significant associations to MetS components and adipocytokines even after adjustment for age and gender, including blood pressure, lipids, glucose and leptin.ConclusionIn conclusion, while SAD is significantly associated with components of MetS among children and adolescents, it is not superior to BMI. The use of SAD therefore may not be practical for use in the pediatric clinical setting. Follow-up studies are needed to determine whether SAD has clinical significance in terms of harder outcomes such as predicting diabetes mellitus or cardiovascular diseases.

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Section: Discussionmentioning

confidence: 99%

Association of body mass index, sagittal abdominal diameter and waist-hip ratio with cardiometabolic risk factors and adipocytokines in Arab children and adolescents

et al. 2012

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“…Abdominal diameter (AD, cm) was defined as the distance from the abdominal subcutaneous fascia to the anterior border of the vertebral body at the same SAD level [25]. Ventral subcutaneous thickness (VST, cm) was the thickness of the subcutaneous adipose tissue at the same SAD and AD level [26]. Dorsal subcutaneous thickness (DST, cm) was defined as the distance between the anterior edge of the subcutaneous fat and the subcutaneous fascia in the L5 or S1 vertebral body perpendicular to the skin at the presacral level [15] (Figure 1).…”

Section: Methodsmentioning

confidence: 99%

Abdominal adipose tissue thickness measured using magnetic resonance imaging is associated with lumbar disc degeneration in a Chinese patient population

Yang

Huang

et al. 2016

Oncotarget

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The relationship between abdominal adiposity and disc degeneration remains largely uninvestigated. Here, we investigated the association between abdominal adipose tissue thickness and lumbar disc degeneration in a cross-sectional study of 2415 participants from The Second Affiliated Hospital of Wenzhou Medical University. All subjects were scanned with a 3T Magnetic Resonance Imaging system to evaluate the degree of lumbar disc degeneration. Multiple logistic regression analysis revealed that men in the highest quartiles for abdominal diameter (AD), sagittal diameter (SAD), and ventral subcutaneous thickness (VST) were at higher odds ratio for severe lumbar disc degeneration than men in the lowest quartiles. The adjusted model revealed that women in the highest quartiles for AD and SAD were also at higher odds ratio for severe lumbar disc degeneration than women in the lowest quartiles. Our results suggest that abdominal obesity might be one of underlying mechanisms of lumbar disc degeneration, and preventive strategies including weight control could be useful to reduce the incidence of lumbar disc degeneration. Prospective studies are needed to this confirm these results and to identify more deeper underlying mechanisms.

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“…Abdominal (central) obesity is associated with dyslipidemia, impaired fasting glucose, insulin resistance and hypertension, which result in increased risk of cardio-and cerebrovascular diseases, and consequently premature death (Guzzaloni, 2009).…”

Section: Abdominal Obesitymentioning

confidence: 99%

Sagittal Abdominal Diameter as the Anthropometric Measure of Cardiovascular Risk

Stokić¹,

Srdić²,

Brtka³

et al. 2012

Recent Advances in Cardiovascular Risk Factors

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Among the non-communicable diseases, cardiovascular disorders are the leading cause of morbidity and mortality in both the developed and the developing countries. The spectrum of risk factors is wide and their understanding is imperative to prevent the first and recurrent episodes of myocardial infarction, stroke or peripheral vascular disease which may prove fatal or disabling. This book has tried to present an update on risk factors incorporating new research which has thrown more light on the existing knowledge. It has also tried to highlight regional diversity addressing such issues. It will hopefully be resourceful to the cardiologists, general practitioners, family physicians, researchers, graduate students committed to cardiovascular risk prevention.

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Sagittal abdominal diameter is more predictive of cardiovascular risk than abdominal fat compartments in severe obesity

Abstract: Objective: To compare the predictive role of abdominal fat distribution by computed tomography (CT) with that of total abdominal fat by sagittal abdominal diameter (SAD) on cardiovascular risk in severe obesity.

Cited by 20 publications

References 37 publications

Association of body mass index, sagittal abdominal diameter and waist-hip ratio with cardiometabolic risk factors and adipocytokines in Arab children and adolescents

Association of body mass index, sagittal abdominal diameter and waist-hip ratio with cardiometabolic risk factors and adipocytokines in Arab children and adolescents

Abdominal adipose tissue thickness measured using magnetic resonance imaging is associated with lumbar disc degeneration in a Chinese patient population

Sagittal Abdominal Diameter as the Anthropometric Measure of Cardiovascular Risk

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