Safety of the haemostatic agent Surgiflo® in excisions of the submandibular gland: our experience in 17 cases

Real‐world surgical outcomes of a gelatin‐hemostatic matrix in women requiring a hysterectomy: a matched case–control study

“…Bannister and Ah‐See reported 17 cases of hemostasis using SURGIFLO ® in patients requiring excisions of the submandibular gland . No complications were reported within the duration of hospital stay but no information was provided on outcomes beyond the discharge from hospital.…”

“…The available literature on SURGIFLO ® is sparse. A PubMed literature search until January 2015 revealed nine publications , four of which are on animal models. Of the five publications describing clinical studies, all but one describes the use in clean surgery .…”

Surgiflo®may have a potential impact on the healing process in cricotracheal resection anastomosis

“…Subsequently, it was concluded that these agents can be used safely in a wide range of head and neck surgeries including laryngectomies and neck dissections, in order to achieve good haemostasis and to prevent bleeding. 1,24 Surgiflo ® consists of Surgifoam powder that is provided in a syringe, which is mixed either with saline or with human thrombin to create an injectable foam. 25 When used alone or with thrombin, gelatin provides a meshwork where the body's endogenous platelets, fibrin and thrombin may be entrapped, facilitating rapid clot formation.…”

“…Two studies reported application of Floseal ® /Surgiflo ® in submandibular sialadenectomy with no postoperative reactions, side‐effects or complications. Subsequently, it was concluded that these agents can be used safely in a wide range of head and neck surgeries including laryngectomies and neck dissections, in order to achieve good haemostasis and to prevent bleeding 1,24 …”

Drainless parotidectomy and the same day discharge with routine use of topical haemostatic agent and Balaclava bandage

“…With emerging evidence on safety profile and effectiveness as an adjunct for bleeding control, topical haemostatic agents are gradually gaining popularity in head and neck surgery . The two haemostats commonly used in our unit are Floseal ® (Baxter Healthcare) and Tisseel ® (Baxter Healthcare), each with different mechanism of action.…”