2006
DOI: 10.5414/cnp66171
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Safety of paracentesis in inpatients

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Cited by 4 publications
(5 citation statements)
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“…Although safety of LVP, in terms of hemodynamic deterioration after therapeutic paracentesis, in patients with cirrhosis and tense ascites has been proven in a randomized controlled trial [22][23][24], this approach has been reported to be associated with an increased risk of acute renal failure and deaths in a hospital-based study [14]. Moreover, a major problem with LVP is that repeated LVPs cause protein and complement depletion from the ascitic fluid compared with diet/diuretic therapy, and this may predispose to ascitic fluid infection.…”
Section: Discussionmentioning
confidence: 98%
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“…Although safety of LVP, in terms of hemodynamic deterioration after therapeutic paracentesis, in patients with cirrhosis and tense ascites has been proven in a randomized controlled trial [22][23][24], this approach has been reported to be associated with an increased risk of acute renal failure and deaths in a hospital-based study [14]. Moreover, a major problem with LVP is that repeated LVPs cause protein and complement depletion from the ascitic fluid compared with diet/diuretic therapy, and this may predispose to ascitic fluid infection.…”
Section: Discussionmentioning
confidence: 98%
“…This, coupled with limited facilities for liver transplantation, transjugular intrahepatic portosystemic shunting, and other high-tech modalities, leads to the necessity to look for alternative means for mobilization of resistant ascites, even if for temporary relief. LVP, though less expensive and relatively less invasive, is nevertheless associated with various complications [13][14][15]. It is, therefore, prudent to sort out more convenient and acceptable treatment option for these patients.…”
Section: Introductionmentioning
confidence: 98%
“…Just as would be the case in an abdominal paracentesis, potential complications include failed procedure, abdominal wall hematoma, spontaneous hemoperitoneum due to mesenteric bleeding, hollow viscus perforation, catheter loss in the abdominal cavity, and major blood vessel laceration. 8 Many of these risks are mitigated in this situation because the increase in abdominal pressure displaces much of the intra-abdominal contents. Furthermore, surgical entry of the abdominal cavity for definitive management allows for evaluation and resolution of many of the possible complications.…”
Section: Discussionmentioning
confidence: 99%
“…12 The heterogeneity in the risk of death is primarily due to a retrospective study of therapeutic paracentesis in hospitalized patients at a tertiary care hospital. 16 The risk of death, renal failure, hyponatremia, and hepatic encephalopathy with therapeutic paracentesis are further discussed in "Results" (see "Plasma Expanders in Therapeutic Paracentesis"). A retrospective analysis of 242 consecutive diagnostic paracenteses reported complicated bowel perforation in 0.83% (95% confidence interval [CI], 0.10%-3.0%) and residual catheter tip fragment in 0.41% (95% CI, 0.01%-2.3%).…”
Section: What Adverse Events Can Results From a Paracentesis?mentioning
confidence: 99%
“…Several prospective and retrospective studies of diagnostic and therapeutic paracentesis report on significant bleeding and death (TABLE 1). The studies are too heterogeneous to allow meaningful metaanalysis but the overall rate of significant bleeding [8][9][10][11][12][13][14][15] ranges from 0% to 2.7% and of death 9,10,12,13,16 from 0% to 17%. Variability in bleeding rates may be influenced by preexisting renal dysfunction.…”
Section: What Adverse Events Can Results From a Paracentesis?mentioning
confidence: 99%