Abstract:The patients with Down syndrome (DS) have been suspected of having some kinds of defects in their immune system (Levin et al. 1979) . Moreover, there have been only a few data on the effect of vaccination on them (Knuutila et al. 1979) . Therefore, the DS patients have been apt to be kept vaccinations off so far. But the vaccination to them should be needed more, since they show a tendency to be severer than normal children when they suffer from infectious diseases, if no particular evil occurs.Materials and… Show more
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