Safety of Herbal Medicines Use: Case Study of Ikorodu Residents in Lagos, Nigeria

Awodele, Olufunsho; Amagon, Kennedy I.; Usman, Sikiru Olatunji; Obasi, Precious C.

doi:10.2174/1574886308666131229104104

Cited by 6 publications

(4 citation statements)

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“…Morbidity and Mortality Associated with Community used Herbal (sagwa)use in Children with Acute Gastroenteritis in Diyala Governorate Ali M Shukur toxicity which is in agreement with previous studies in Nigeria and S. Africa [30,35]. The clinical consequences from hospitalization, follow up till discharge, where most of children with sagwa necessitate emergency room visit as well as emergency room and respiratory care unit in comparison to control group; this is mostly due to detrimental effect of sagwa use.…”

Section: Issue 2decsmber 2019supporting

confidence: 88%

Morbidity and Mortality Associated with Community used Herbal (sagwa)use in Children with Acute Gastroenteritis in Diyala Governorate

Shukur¹,

Alezzi²,

Kadhim³

2019

DJM

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Background: Gastroenteritis causes around (28%) of all mortalities among children less than 5 yr old. In our country herbal use (called sagwa in Iraq) is one of line of treatment of gastroenteritis mostly in the rural areas. Objective: To determine the morbidity and mortality of herbal use in acute gastroenteritis in children. Patients and Methods: Two hundred patients involved in a prospective case control study conducted in the Al-Batool Pediatrics, Obstetrics and Gynecology Teaching Hospital, Diyala, Iraq, during a period of six months from August 2017 to February 2018. Results: There is significant association of sagwa use with the rural residency 81(81%), mother education level 57(57%) illiterate mother), the order of the child in the family 13(13%)1st child; the least), diarrhea complications (regarding central nervous system 43(43%), cardiac 58(58%), renal 49(49%) and metabolic 83(83%), hospital stay and condition deterioration and the mortality rate was 9(9%) in sagwa group .Sagwa toxicity is positively proportional to the number of doses 57(57%) in 3rd dose & more) given to children and grandmothers 66(66%) were the principle person who decided to use sagwa in children with diarrhea. The chemical analysis was done in (10) samples only which revealed that heavy metal like lead, cadmium and mercury; that exceed the permissible level. Conclusion: There is significant morbidity and mortality caused by (sagwa) use in children with acute gastroenteritis.

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Section: Issue 2decsmber 2019supporting

confidence: 88%

Morbidity and Mortality Associated with Community used Herbal (sagwa)use in Children with Acute Gastroenteritis in Diyala Governorate

Shukur¹,

Alezzi²,

Kadhim³

2019

DJM

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“…However, recent studies have reported the high use of HMs in Nigeria. [16][17][18][19][20] A study conducted in one of the local government areas (Ekiti state) reported 74.3% of the respondents used HM in the treatment of malaria. 16 In another study, in urban Lagos Nigeria, 66.8% (n=388 respondents) used HM for management of various ailments.…”

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confidence: 99%

Prevalence, determinants and knowledge about herbal medicine and non-hospital utilisation in southwest Nigeria: a cross-sectional study

Aina¹,

Gautam²,

Simkhada³

et al. 2020

BMJ Open

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ObjectivesTo examine the prevalence, determinants, safety perceptions, effectiveness and knowledge of herbal medicines (HMs) and reasons for non-hospital utilisation.DesignCross-sectional study.SettingEkiti state, southwest Nigeria.ParticipantsA representative sample (n=1600) of adults (18 years or above) currently living in Ekiti state, southwest Nigeria for at least 2 years, at the time of study.ResultsThe majority of the respondents (85% n=1265) have used HMs in the last 2 years. Across economic classes use, middle income (88.3%) was the highest (p<0.001), suggesting poverty is not a major factor, even with income inequality. Their use was the most common among respondents with a primary level of education (91.4%, p=0.001); and 100% use (p=0.009) of respondents practising African traditional religion; farmers and those 70 years or above. Our study also reveals more men (p<0.001) used HMs (89.9%) than women (78.6%) and effectiveness was a major reason for use (39.6%) followed by affordability (31.9%). Although the majority of the respondents (90%) knew the difference between certified and uncertified HMs, uncertified ones were the most commonly used (37.3%) in the population.ConclusionAlthough there is a cultural history of HM use within the study population, the choice of use was based on their effectiveness. Therefore, a scientifically valid analysis of this claim within the study population may help achieve a cheaper and affordable healthcare alternative which will be safe. This is important, considering that uncertified HMs were chosen over certified ones, even though a large majority of respondents were aware of differences and likely consequences. This study highlights the need for further investment by the government, individuals and corporate stakeholders in HM research and improvement of conventional healthcare system. This is in addition to public health awareness on the danger of use of uncertified herbal products.

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“…18 End-users of these formulations consumes it indiscriminately unaware of attendant health risks. 19 To protect the uninformed public from the adverse effects of arbitrary application of herbal medicine, health policies grounded on scientific research on the systemic effects of plant extracts is imperative. Aspilia africana has been traditionally used to treat wounds.…”

Section: Resultsmentioning

confidence: 99%

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2019

TJNPR

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Medicinal plants as sources of bioactive agents continue to exhibit fascinating ability in terms of human health management since ancient times with more than half of modern therapeutics in circulation being of natural product origin. 1 The vital role of medicinal herbs in the treatment and prevention of diseases is not by itself an assurance of safety if not properly used by an uninformed public. 2 Aspilia Africana, is a tropical, semi-woody perennial herb belonging to the family, asteracea. It is used by traditional communities in Africa and Asia as a bactericidal, anti-inflammatory, astringent and wound-healing agent. 3,4 Oral consumption of the decoction of the leaves is reportedly able to relieve febrile headache, quicken delivery and cure lumbago, sciatica and stomach disorders. 5-7 Besides management of stomach disorder, others have reported that in folklore medical practice, Aspilia africana herbal preparations can be used for the treatment of stomach aches, dysmenorrhoea, tuberculosis, rheumatoid arthritis, gonococal infection, corneal opacity, cough and insect bites. 8 The kidney performs functions

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Safety of Herbal Medicines Use: Case Study of Ikorodu Residents in Lagos, Nigeria

Cited by 6 publications

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Morbidity and Mortality Associated with Community used Herbal (sagwa)use in Children with Acute Gastroenteritis in Diyala Governorate

Morbidity and Mortality Associated with Community used Herbal (sagwa)use in Children with Acute Gastroenteritis in Diyala Governorate

Prevalence, determinants and knowledge about herbal medicine and non-hospital utilisation in southwest Nigeria: a cross-sectional study

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