Safety of Chorionic Villus Biopsy

Jackson, Laird G.; Wapner, Ronald J.; Barr, Marie

doi:10.1016/s0140-6736(86)91741-1

Cited by 27 publications

(16 citation statements)

References 9 publications

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“…Published reports demonstrate that first trimester diagnosis by chorionic villus sampling (CVS) is safe and reliable enough to be offered in highly skilled centers that also provide extensive counselling [Jahoda et al, 1985;Hogge et al, 1986;Jackson, 1986a;Jackson et al, 1986;Brambati et al, 1987aBrambati et al, , 1988aLeschot et al, 1987;Monni et al, 19871. Recently, the fetal loss rate associated with transcervical chorionic tissue aspiration has been evaluated in a Canadian randomized trial, and no significant difference in loss rates was found between CVS and amniocentesis [Canadian Collaborative CVSAmniocentesis Clinical Trial Group, 19891.…”

Section: Introductionmentioning

confidence: 99%

Transabdominal and transcervical chorionic villus sampling: Efficiency and risk evaluation of 2,411 cases

1990

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Efficacy and risks of transcervical and transabdominal chorionic villus sampling (CVS) methods were evaluated in 1,501 and 910 cases, respectively. We reported a success rate of more than 99% for both sampling procedures and obtained an adequate amount of chorionic tissue in more than 96% of cases on the first attempt. However, the transcervical method was more difficult to learn and was contraindicated by a higher number of unfavorable clinical and anatomical conditions. Transabdominal sampling proved to be a less time-consuming procedure and could also be used after the 12th week of gestation. Bleeding/spotting (10.1%) and uterine cramping (2.5%) were the most frequent early complications following transcervical and transabdominal sampling, respectively. Uterine infection was rare (0.13%) and was reported only after cervical aspiration. No significant effects on fetal growth, preterm delivery, placenta disorders, congenital defects, and perinatal mortality following transcervical and transabdominal sampling, and for both procedures total fetal loss rate was less than 4%. This experience suggests that transabdominal needle sampling is the method of choice; however, transcervical aspiration appears more likely to succeed in a limited number of well-defined conditions.

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Section: Introductionmentioning

confidence: 99%

Transabdominal and transcervical chorionic villus sampling: Efficiency and risk evaluation of 2,411 cases

1990

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“…Die Gesamtrate an Komplikationen lag in einer WHO-Registratur mit fiber 10 700 Ffillen unter 5% [18,19]. Fruchtwasserabgang mit anschliegendem Abort wurde in einer Serie von 864 Chorionzottenbiopsien in 2% berichtet [18,19].…”

Section: Komplikationenunclassified

“…Fruchtwasserabgang mit anschliegendem Abort wurde in einer Serie von 864 Chorionzottenbiopsien in 2% berichtet [18,19]. Schwere Infektionen wurden in dieser Serie nicht beobachtet [18,19]. Brambati und Varotto (1985) empfehlen grundsfitzlich die prfidiagnostische Cervixbakteriologie und evtl.…”

Section: Komplikationenunclassified

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Stand der Chorionzottenbiopsie in der BRD

Weitzel¹

1987

Arch Gynecol Obstet

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“…Until spring 1988 more than 40,000 chorionic villi samplings (CVS) have been documented [Jackson, 19881. Several single institutions reported series with more than 1,000 cases [Simoni et al, 1986;Jackson et al, 1986;Hogge et al, 1986;Sachs et al, 19881. Despite the still unsettled question of the procedure's safety, CVS is currently being offered as an alternative to amniocentesis in many centers.…”

Section: Introductionmentioning

confidence: 99%

Validity of cytogenetic analyses from trophoblast tissue throughout gestation

Miny

Başaran

et al. 1989

Am. J. Med. Genet.

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Cytogenetic findings in the Münster Chorionic Villi Sampling (CVS) program are presented after 1,184 first trimester transcervical samplings and 131 second and third trimester placentacenteses. In the first trimester series the abnormality rate is low (2.4%) in patients with only an age-dependent aneuploidy risk. In this group terminations were performed in only 1.6% because of aneuploidy. True mosaicism was found more frequently after CVS, and the risk of maternal cell contamination seems higher as compared to amniocentesis. There are no obvious differences in the overall rate of diagnostic errors after both procedures, when metaphases after direct preparation and chorionic cell cultures are analysed and doubtful findings such as mosaicism are adequately followed up by amniocentesis. The cytogenetic techniques also offer a very rapid approach to karyotyping in the second and third trimester. We found a high rate of aneuploidy (15%) when placentacentesis was performed after sonographic diagnosis of fetal abnormalities. We conclude that cytogenetic analysis from trophoblast tissue is an accurate diagnostic tool applicable from first to third trimester of pregnancy.

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Safety of Chorionic Villus Biopsy

Cited by 27 publications

References 9 publications

Transabdominal and transcervical chorionic villus sampling: Efficiency and risk evaluation of 2,411 cases

Transabdominal and transcervical chorionic villus sampling: Efficiency and risk evaluation of 2,411 cases

Stand der Chorionzottenbiopsie in der BRD

Validity of cytogenetic analyses from trophoblast tissue throughout gestation

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