Safety evaluation of a polyherbal formulation: Acute and sub-acute toxicity study using Wistar Albino rats
Vaibhav Tripathi,
Chandra Kishore Tyagi,
Wasim Raja
Abstract:Vatrog Nashak Churna (VNC) is a traditional polyherbal formulation for musculoskeletal diseases. Although the safety and mechanism of toxicity of the individual herbs have been explored, the formulation remains undocumented in the literature. Research into its sub-acute toxicity will strengthen its pharmacological outline and encourage its investigation as a potential future treatment. Rats were split into three groups (n¼12) by OECD TG 407 (OECD, 2008). The limit test determined the necessary amount of VNC. T… Show more
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