His column investigates important developments that are making-or are about to make-the transition from the laboratory to clinical practice, as well as technologies and approaches that have recently made that jump. The author (BKP) is an employee of the US Government and this work was prepared as part of his official duties. As such, there is no copyright to transfer. The views expressed in this article are his own and do not necessarily reflect the official policy or position of the Department of the Army, Department of the Navy, Department of Defense, nor the US Government. He certifies that all individuals who qualify as authors have been listed and that he alone has participated in the writing of the document, and that the document represents valid work. If he used information derived from another source, he obtained all necessary approvals to use it and made appropriate acknowledgements in the document. Nothing in the presentation implies any Federal/DOA/DON/DOD endorsement. The author has received no financial support for this column. All ICMJE Conflict of Interest Forms for authors and Clinical Orthopaedics and Related Research ® editors and board members are on file with the publication and can be viewed on request. The opinions expressed are those of the writer, and do not reflect the opinion or policy of CORR ® or The Association of Bone and Joint Surgeons ® . Clinical Orthopaedics and Related Research ® neither advocates nor endorses the use of any treatment, drug, or device. Readers are encouraged to always seek additional information, including FDA approval status, of any drug or device before clinical use.