Safety Assessment of Phosphoric Acid and Its Salts as Used in Cosmetics

Johnson, Wilbur; Boyer, Ivan; Bergfeld, Wilma F.; Belsito, D.; Hill, Ronald A.; Klaassen, Curtis D.; Liebler, D.C.; Marks, James G.; Shank, Ronald C.; Slaga, Thomas J.; Snyder, Paul W.; Gill, Lillian J.; Heldreth, Bart

doi:10.1177/10915818211014499

Cited by 3 publications

(2 citation statements)

References 54 publications

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“…In the context of the safety for the users, the literature search identified one relevant publication (Johnson Jr et al., 2021 ), in which phosphoric acid and its salts were evaluated as cosmetic ingredients, confirming the corrosive properties of orthophosphoric acid.…”

Section: Assessmentmentioning

confidence: 99%

Assessment of the feed additive consisting of orthophosphoric acid for all animal species for the renewal of its authorisation (Prayon S.A.; Chemische Fabrik Budenheim KG; BK Giulini GmbH)

Bampidis,

Azimonti,

Bastos

et al. 2023

EFS2

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Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the application for renewal of orthophosphoric acid as a technological additive (functional group: preservatives) for all animal species. The applicant has provided evidence that the additive currently on the market complies with the existing conditions of authorisation. There is no evidence that would lead the FEEDAP Panel to reconsider its previous conclusions. Thus, the Panel concluded that the additive remains safe for all animal species provided that the optimal Ca:P ratio is maintained. Additionally, the FEEDAP Panel concluded that orthophosphoric acid remains safe for the consumer and the environment under the authorised conditions of use. Regarding the user safety, orthophosphoric acid is corrosive to the skin and eyes and should be considered as hazardous to the respiratory tract. There is no need for assessing the efficacy of the additive in the context of the renewal of the authorisation.

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Section: Assessmentmentioning

confidence: 99%

Assessment of the feed additive consisting of orthophosphoric acid for all animal species for the renewal of its authorisation (Prayon S.A.; Chemische Fabrik Budenheim KG; BK Giulini GmbH)

Bampidis,

Azimonti,

Bastos

et al. 2023

EFS2

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“…6,7 For complete and detailed information, please refer to the original documents, which are available on the Cosmetic Ingredient Review (CIR) website (https://www.cir-safety.org/ ingredients). Some of the constituent acids or salts, related to the zinc salt ingredients in this report, have been reviewed previously by the Panel; a summary of safety conclusions for those ingredients [2][3][4][5][8][9][10][11][12][13][14][15][16][17][18] is included in this report (Table 2). Those original reports are also available on the CIR website.…”

mentioning

confidence: 99%

Safety Assessment of Zinc Salts as Used in Cosmetics

Scott,

Fiume,

Zhu

et al. 2024

Int J Toxicol

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The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 27 inorganic and organometallic zinc salts as used in cosmetic formulations; these salts are specifically of the 2+ (II) oxidation state cation of zinc. These ingredients included in this report have various reported functions in cosmetics, including hair conditioning agents, skin conditioning agents, cosmetic astringents, cosmetic biocides, preservatives, oral care agents, buffering agents, bulking agents, chelating agents, and viscosity increasing agents. The Panel reviewed the relevant data for these ingredients, and concluded that these 27 ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating.

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