Some patients with keratoconus have poor corrected distance visual acuity (CDVA) associated with high refractive errors. According to our treatment protocol, 1 the best approach for these cases is intracorneal ring segments (ICRS) implantation (usually one segment) to improve CDVA followed by corneal collagen cross-linking (CXL) treatment 4 weeks later to stabilize the cornea and phakic toric implantable collamer lens (TICL) (Visian Toric V4b ICL; STAAR Surgical, Monrovia, CA) implantation 4 to 6 months after CXL to correct the residual refractive errors. We conducted a retrospective analysis of 11 eyes of 7 patients with moderate to severe keratoconus (according to the Amsler-Krumeich classifi cation 2 , 4 eyes had stage II keratoconus and 7 eyes had stage III) and poor CDVA who underwent three-step ICRS implantation-CXL-TICL implantation procedures at our eye hospital. The two procedures (ICRS implantation-CXL) were performed sequentially at an interval of 4 weeks and TICL implantation was performed at least 6 months after CXL. Data were collected preoperatively, at the 6-month follow-up visit after sequential ICRS implantation-CXL, and at the 6-month follow-up visit after TICL implantation.Mean age was 29.20 years (range: 22 to 46 years). Uncorrected distance visual acuity (UDVA) showed signifi cant improvement after three sequential procedures (mean UDVA improved from 1.47 ± 0.38 log-MAR at baseline to 1.13 ± 0.50 logMAR after ICRS implantation-CXL procedures and to 0.27 ± 0.20 logMAR after ICL implantation). Overall, 63.7% of eyes (7 of 11) had UDVA greater than 20/40 by 6 months after ICL insertion. CDVA also showed signifi cant change 6 months after ICRS implantation-CXL (CDVA improved from 0.50 ± 0.22 logMAR at baseline to 0.29 ± 0.23 log-MAR 6 months after ICRS implantation-CXL). However, CDVA did not show any signifi cant improvement after ICL insertion (0.19 ± 0.11 logMAR).Refraction signifi cantly improved after the three procedures. The spherical equivalent changed significantly from -9.70 ± 3.1 diopters (D) at baseline to -7.65 ± 3.23 D 6 months after ICRS implantation-CXL and to -0.58 ± 1.01 D 6 months after TICL implantation. The cylindrical component also changed signifi cantly from 3.81 ± 1.15 D at baseline to 1.84 ± 0.35 D 6 months after ICL insertion. However, no signifi cant change was noted in cylindrical component 6 months after ICRS implantation-CXL (3.81 ± 1.15 D at baseline vs 4.06 ± 1.58 D 6 months after ICRS implantation-CXL). Keratometric readings (central corneal power obtained by topography) decreased after ICRS implantation-CXL: mean K (fl at) decreased from 48.51 ± 4.26 D at baseline to 45.19 ± 3.98 D 6 months after ICRS implantation-CXL and mean K (steep) decreased from 54.24 ± 4.96 D at baseline to 50.41 ± 4.32 D 6 months after ICRS implantation-CXL. Mean K (max) decreased from 57.41 ± 6.32 D at baseline to 54.01 ± 4.75 D 6 months after ICRS implantation-CXL.In this retrospective study, all patients had poor CDVA and ICRS insertion (performed using femtosecond laser to create t...