Safety and Efficacy of the Alexandrite Laser for the Treatment of Renal and Ureteral Calculi

Pearle, Margaret S.; Sech, Scott M.; Cobb, Charles G.; Riley, Joseph R; Clark, Patrick J.; Preminger, Glenn M.; Drach, George W.; Roehrborn, Claus G.

doi:10.1016/s0090-4295(97)00492-5

Cited by 28 publications

(10 citation statements)

References 35 publications

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“…The first commercially successful laser lithotrite was the coumarin pulse dye laser but it could not fragment cystine stones. In clinical use the pulsed dye laser has been safe and effective in Nd: YAG and Alexandrite lasers [5,6]. The holmium: YAG (Ho: YAG) laser is the newest wavelength device available for urological applications.…”

Section: Introductionmentioning

confidence: 99%

Holmium : YAG Laser for Intra Corporeal Lithotripsy

Sandhu

Srivastava

Madhusoodanan

et al. 2007

Medical Journal Armed Forces India

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Section: Introductionmentioning

confidence: 99%

Holmium : YAG Laser for Intra Corporeal Lithotripsy

Sandhu

Srivastava

Madhusoodanan

et al. 2007

Medical Journal Armed Forces India

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“…Planning the research design, werelied on experimental and clinical facts, obtained earlier, notably: during the experiment the new electro pulse RCL method demonstrated high effectiveness in analogous sandcement mixture stone models destruction, including the samples consisting of 100% cement, during the singular pulse exposure with the power of 0.1 to 0.45 J [8,9]. Such pulse power is comparable with the power of pulses, generated by the most safe RCL types, the pneumatic and laser ones (0.1 -0.14 J and 0.12 -0.5 J, respectively) [1,4,6,7,10].…”

Section: Discussionmentioning

confidence: 99%

“…In the recent decade during the urolithiasis treatment the accent is made on the usage of modern low-invasive approaches like endourologic methods, mainly retrograde contact lithotripsy (RCL) [1][2][3][4]. In 2006 the electro pulse method which was offered as a new way of contact lithotripsy, which looked like splitting up the nephrolith by the exposure of the solid body by the electro pulses of nanosecond duration [5].…”

Section: Introductionmentioning

confidence: 99%

The morphologic changes in the wall of the human urinary tracts after direct electro pulse exposure: the in vitro research

Gudkov¹,

Boshchenko²,

Недосеков³

2013

RusOMJ

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Abstract:The aim -study of the morphological changes in the wall of the human urinary tracts, developing after direct electro pulse exposure (DEPE). Materials and methods -The fragments of the surgical material obtained after the pelvis (n=25), ureter (n=33) and urinary bladder (n=20) open operations, were used in the research. DEPE was carried out by single (from 1 to 20) nanosecond pulses with the power of 0.8 J (joule) and 1.0 J made by the electro pulse "Urolit-105M" lithotriptor probe on the fragments' mucous tunic placed in the Petri dishes with 0.9% NaCl solution. The fragments were fixed in the formalin and after the processing, and pouring with paraffin, the tissue slices were prepared. Results -The kidney pelvis wall, where changes like epithelium desquamation, the basal membrane disorganization, paretic capillary expansion did not go beyond sub mucous layer even after exposure by 10 pulses with the power 1.0 J each, aimed at one point, proved to be the most resistant to DEPE. In the fragments of ureter and urinary bladder the same changes were detected after exposure by 5 pulses with the power of 1.0 J each, whereas after exposure by 10 pulses with the power 1.0 J each the changes occurred which were restricted by the muscular layer. Conclusion -The DEPEon the mucous tunic of the isolated urinary tracts fragments by the means of 10 pulses with the power of 1.0 J each looks safe, causes morphologic changes, restricted by the muscular layer and does not lead to the wall perforation.

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“…The alexandrite laser was introduced in 1991 and even though initial results were promising, there was never widespread acceptance of this laser for use as a lithotriptor [Pearle et al 1998]. …”

Section: Stonesmentioning

confidence: 99%

The evolution of lasers in urology

Zarrabi

Gross

2011

Therapeutic Advances in Urology

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The world's first laser was developed by Theodore Maiman in 1960. Over the course of the past five decades, this technology has evolved into a highly specialized entity, also finding a niche market in the field of urology. Lasers obtained from various lasing mediums producing amplified light of different wavelengths have been tested for urological applications. Today, these lasers are most commonly used in the surgical management of benign prostatic hyperplasia and as intracorporeal lithotripters. Other uses include ablation of various urologic tumors and incising strictures of the upper-and lower urinary tract. A continuous process of evolution of this technology is taking place, resulting in surgical lasers becoming ever safer, more effective, and more affordable.

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Safety and Efficacy of the Alexandrite Laser for the Treatment of Renal and Ureteral Calculi

Cited by 28 publications

References 35 publications

Holmium : YAG Laser for Intra Corporeal Lithotripsy

Holmium : YAG Laser for Intra Corporeal Lithotripsy

The morphologic changes in the wall of the human urinary tracts after direct electro pulse exposure: the in vitro research

The evolution of lasers in urology

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