Safety and Efficacy of Single-site Phacotrabeculectomy With Mitomicin C Using Nylon and Polyglactin Suture for Scleral Tunnel Closure

Vijaya, Lingam; David, Rathini Lilian

doi:10.1097/ijg.0000000000000066

Cited by 4 publications

(1 citation statement)

References 11 publications

(13 reference statements)

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“…Phacotrabeculectomy again not only improves vision but reduces the need for sequential surgery. [12][13][14] However, some surgeons prefer separate procedures over combined. So there is lack of consensus on the best approach in such cases.…”

Section: Introductionmentioning

confidence: 99%

Outcome of Intraoperative Mitomycin C Injection in Trabeculectomy and Phacotrabeculectomy in Patients with Glaucoma

Farooq

Farooq²,

Faisal³

2021

pak J Ophthalmol

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Purpose: To determine the efficacy and safety of per-operative mitomycin C injection during trabeculectomy and combined phaco-trabeculectomy in different types of glaucoma. Study Design: Interventional case series. Place and Duration of Study: Shifa International, between January 2018 to July 2020. Methods: Thirty one patients requiring trabeculectomy or Phaco-trabeculectomy with mitomycin C because of maximum tolerable anti-glaucoma treatment or poor compliance were included in the study. Out of these 15 in group A underwent simple trabeculectomy with intra-operative mitomycin C and 16 patients in group B underwent phacotrabeculectomy with intra-operative mitomycin C and IOL implantation. All patients underwent an eye examination (including IOP and visual acuity) before surgery and then afterwards at 1 week, 1 month, 2 months, 6 months and 1 year. Main outcome measures were best corrected visual acuity, intra-ocular pressure and number of medications at base line and post-operatively. Results: Demographic results of the two groups were similar. Mean follow-up period was 1 year, mean IOP was 11 in group Aand 15.5 in group B in last follow-up.Mean IOP reduction at 1 year was significant in both group A and B (p = 0.001, p = 0.022 respectively). Hypotony, post-operative inflammatory membrane and bleb fibrosis were the main complications in group A and group B. Conclusion: Trabeculectomy with mitomycin C and phaco-trabeculectomy with mitomycin C are equally successful at lowering IOP in common types of glaucoma permitting significant and safe reduction of anti-glaucoma medications for atleast 1 year after surgery. Key Words: Mitomycin, Glaucoma, Intra ocular pressure.

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Section: Introductionmentioning

confidence: 99%

Outcome of Intraoperative Mitomycin C Injection in Trabeculectomy and Phacotrabeculectomy in Patients with Glaucoma

Farooq

Farooq²,

Faisal³

2021

pak J Ophthalmol

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Success rates of 2-site phacoemulsification combined with fornix-based trabeculectomy using mitomycin C for primary angle-closure glaucoma and primary open-angle glaucoma in an Asian population

et al. 2017

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Phacotrabeculectomy in Eyes With Uveitic Glaucoma: A Retrospective Case-Control Study

Wadke¹,

Vijaya²,

George³

et al. 2019

Journal of Glaucoma

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Precis: Phacotrabeculectomy with adjunctive mitomycin C is a good option for the management of coexisting cataract and glaucoma. Strict preoperative control of inflammation and close follow-up are essential in the management of eyes with uveitic glaucoma (UG). Purpose: The purpose of this study was to compare the outcomes of phacotrabeculectomy with adjunctive antimetabolites in the management of patients with UG and patients with primary open-angle glaucoma (POAG). Materials and Methods: A retrospective case-control study of 112 patients with UG and 120 patients with POAG who underwent phacotrabeculectomy with mitomycin C and had a follow-up of ≥12 months between January 2000 and June 2015 was performed. Patients who had undergone intraocular surgery or cyclodestructive procedures earlier were excluded. The primary outcome was intraocular pressure (IOP) control; secondary outcomes included visual acuity and complication rates. Results: IOP control was similar at the final visit in the UG group (14.52±6.74 mm Hg) and the POAG group (14.39±4.18 mm Hg) (P=0.867). Kaplan-Meier survival analysis showed a cumulative probability of survival (IOP: 6 to 18 with or without medications) in 71% and 77% at the end of 5 years (P=0.094) in the UG and POAG groups, respectively. Visual outcomes were worse in the UG group (0.5±0.68 logMAR units), as compared with the POAG group (0.27±0.47 logMAR units) (P=0.002). Complications such as cystoid macular edema (P=0.025) and posterior capsular opacification (P=0.004) were more common in the UG group. Recurrence of inflammation occurred in 34 eyes (30.04%) in the UG group. Conclusion: Meticulous control of perioperative and postoperative inflammation could have contributed to the favorable long-term outcomes of phacotrabeculectomy in UG, as compared with POAG.

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Safety and Efficacy of Single-site Phacotrabeculectomy With Mitomicin C Using Nylon and Polyglactin Suture for Scleral Tunnel Closure

Abstract: The technique used here seems to be effective in controlling the IOP and has very minimal associated complications.

Cited by 4 publications

References 11 publications

Outcome of Intraoperative Mitomycin C Injection in Trabeculectomy and Phacotrabeculectomy in Patients with Glaucoma

Outcome of Intraoperative Mitomycin C Injection in Trabeculectomy and Phacotrabeculectomy in Patients with Glaucoma

Success rates of 2-site phacoemulsification combined with fornix-based trabeculectomy using mitomycin C for primary angle-closure glaucoma and primary open-angle glaucoma in an Asian population

Phacotrabeculectomy in Eyes With Uveitic Glaucoma: A Retrospective Case-Control Study

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