Safety and efficacy of biological therapy with TNF-inhibitors and non TNF-inhibitors in a cohort of young adults affected by juvenile idiopathic arthritis (JIA): data from a single centre experience
Abstract:AimTo evaluate safety and efficacy in young adults with JIA treated by TNF and non anti-TNF inhibitors.Methods 36 patients (F26-M10, median age 18,8 yrs) with JIA treated with anti-TNF (17 etanercept, 4 infliximab, 15 adalimumab) followed at Transition Clinic of Florence from January 2008 to December 2010 were enrolled in a observational, singlecentre, retrospective study. 12 pts (4 etanercept, 4 infliximab, 4 adalimumab) failed to respond or did not tolerate the first therapy and switched to a second one. Mor… Show more
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