Sacroplasty for Local or Massive Localization of Multiple Myeloma

Basile, Antonio; Tsetis, Dimitrios; Cavalli, Maide; Fiumara, Paolo; Raimondo, Francesco Di; Coppolino, Francesco; Coppolino, Carmelo; Mundo, Elena; Desiderio, Carla; Granata, Antonio; Patti, Maria Teresa

doi:10.1007/s00270-009-9761-x

Cited by 22 publications

(9 citation statements)

References 10 publications

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“…In our patients the pain reduction lasted up to 6 months postoperatively. Basile et al [18] and Wee et al [13] show similar results for patients with multiple myeloma. A further advantage for cancer patients is that the alleviation of the strong pain symptoms makes it much easier to perform other necessary measures such as radiotherapy and chemotherapy.…”

Section: Abb 1 Illustration Der Möglichen Zugangswege Zur Erreichungmentioning

confidence: 59%

Balloon Sacroplasty as a Palliative Pain Treatment in Patients with Metastasis-Induced Bone Destruction and Pathological Fractures

Andresen

Radmer²,

Lüdtke

et al. 2014

Fortschr Röntgenstr

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Purpose: In the case of metastatic involvement of the sacrum with destruction and consecutive pathological fracture, intense disabling pain is one of the defining factors. The feasibility, safety and pain development with cement augmentation were to be investigated. Materials and Methods: CT-guided balloon sacroplasty was conducted in 10 patients with metastasis-induced bone destruction of the sacrum. After establishment of the entry point, a K-wire was first introduced as far as the central tumor lesion via the short, or transiliac axis. A cannula was then positioned over the wire. Under CT guidance, a balloon catheter was introduced through the cannula and inflated and deflated several times. The PMMA cement was then injected into the preformed cavity. The procedure was completed by a spiral CT control using the thin-slice technique. Pain intensity was determined using a visual analog scale (VAS) before the procedure, on the 2nd postoperative day and 6 months after the intervention. Finally, the patients were asked to state how satisfied they were. Results: Balloon sacroplasty was technically feasible in all patients. The control CT scan showed central distribution of the cement in the tumor lesion. On average 6?+/??1.78 (4???10) ml of PMMA cement were introduced per treated lesion. A significant (p?

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Section: Abb 1 Illustration Der Möglichen Zugangswege Zur Erreichungmentioning

confidence: 59%

Balloon Sacroplasty as a Palliative Pain Treatment in Patients with Metastasis-Induced Bone Destruction and Pathological Fractures

Andresen

Radmer²,

Lüdtke

et al. 2014

Fortschr Röntgenstr

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“…Balloon-assisted sacroplasty may prevent polymethylmethacrylate (PMMA) migration, as kyphoplasty does for vertebral compression fracture11). In metastasis, multiple myeloma, and pelvic radiation necrosis as well, sacroplasty can provide pain relief4,10,25).…”

Section: Discussionmentioning

confidence: 99%

Effects of Percutaneous Sacroplasty on Pain and Mobility in Sacral Insufficiency Fracture

Choi

Shin

Lee

et al. 2017

J Korean Neurosurg Soc

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ObjectiveSacral insufficiency fracture (SIF) contributes to severe low back pain. Prolonged immobilization resulting from SIF can cause significant complications in the elderly. Sacroplasty, a treatment similar to vertebroplasty, has recently been introduced for providing pain relief in SIF. The purpose of this study is to investigate the clinical short-term effects of percutaneous sacroplasty on pain and mobility in SIF.MethodsThis study is conducted prospectively with data collection. Sixteen patients (3 men and 13 women) with a mean age of 77.5 years (58 to 91) underwent sacroplasty. Patients reported visual analogue scale (VAS; 0–10) and Oswestry disability index (ODI; 0–100%) scores. VAS and ODI scores were collected preoperatively and again at one day, one month, and three months postoperatively. Questionnaires measuring six activities of daily living (ADLs) including ambulating, performing housework, dressing, bathing, transferring from chair, and transferring from bed were collected. Ability to perform ADLs were reported preoperatively and again at three months postoperatively.ResultsThe mean preoperative VAS score (mean±SD) of 7.5±0.8 was significantly reduced to 4.1±1.6, 3.3±1.0, and 3.2±1.2 postoperatively at one day, one month, and three months, respectively (p<0.01). The mean ODI score (%) also significantly improved from 59±14 preoperatively to 15.5±8.2 postoperatively at one month and 14.8±8.8 at three months (p<0.01). All ADL scores significantly improved at three months postoperatively (p<0.01).ConclusionPercutaneous sacroplasty alleviates pain quickly and improves mobility and quality of life in patients treated for SIF.

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“…also demonstrated an improvement in Performance Status (PS) and reduced analgesic dose constant in follow-up. 23…”

Section: Discussionmentioning

confidence: 99%

Percutaneous sacroplasty for the management of painful pathologic fracture in a multiple myeloma patient: Case report and review of the literature

2016

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Percutaneous kyphoplasty has a well-established role in the treatment of pathologic fractures in patients with multiple myeloma. Despite this, there is a scarcity of literature surrounding its use and efficacy in the sacrum. We present a case of successful symptom resolution in a patient with painful sacral fracture following sacroplasty, and review the existing literature. An 81-year-man with multiple myeloma presented to the hematology/oncology clinic with a history of excruciating pain while seated. The impact of this pain on his quality of life subjectively was rated to be particularly high. Computed tomography of the sacrum confirmed the presence of pathologic fracture within the S1 and S2 vertebrae. Under fluoroscopic guidance, polymethyl methacrylate (PMMA) bone cement was injected via 11-gauge needles using an anterior-oblique approach. No immediate post-procedural complications occurred, such as foraminal extravasation or venous injection. The patient reported himself to be pain-free 1 day following the procedure, and this remains the case to date at 2 years of follow-up. Sacroplasty is technically feasible and can provide durable relief of symptoms in patients with painful pathologic fractures of the sacrum. It is likely underused and can offer tremendous benefit to myeloma patients.

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Sacroplasty for Local or Massive Localization of Multiple Myeloma

Cited by 22 publications

References 10 publications

Balloon Sacroplasty as a Palliative Pain Treatment in Patients with Metastasis-Induced Bone Destruction and Pathological Fractures

Balloon Sacroplasty as a Palliative Pain Treatment in Patients with Metastasis-Induced Bone Destruction and Pathological Fractures

Effects of Percutaneous Sacroplasty on Pain and Mobility in Sacral Insufficiency Fracture

Percutaneous sacroplasty for the management of painful pathologic fracture in a multiple myeloma patient: Case report and review of the literature

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