P ilonidal sinus disease (PSD) is a common, chronic inflammatory disease of the skin and subcutaneous fatty tissue. PSD most often involves the sacrococcygeal region but can occur on the fingers or navel. PSD is mostly observed in a young adult male and is responsible for significant work and school absenteeism. [1] PSD was first described by Mayo in 1833, and the first treatments were described by Anderson in 1844. [2] Symptoms may vary from asymptomatic pits to abscesses that require drainage. [3] The aetiology of PSD has been an ongoing subject of debate, but it is currently thought to be acquired. [4] In 1992, Karydakis described the involvement of the skin and hair in the deep intergluteal cleft in the development of PSD. [5] This study evaluated the effects of hypertrichosis, family history, obesity and sex steroids in 298 patients with PSD.
MethodsThe medical records of 618 patients treated at the General Surgery Clinic of Malatya State Hospital for primary PSD between January 2014 and December 2017 were evaluated retrospectively. Three patients with psychiatric disorders, five with diabetes mellitus, seven with active abscesses, six receiving steroid therapy for other medical conditions and 13 without regular clinical follow-up were excluded from Objectives: Pilonidal sinus disease causes chronic inflammation of the skin and subcutaneous fatty tissue, and it commonly localises in the sacrococcygeal region. This study evaluated the effects of hypertrichosis, family history, obesity and sex steroids in 298 patients with pilonidal sinus disease. Methods: The medical records of 618 patients treated at the General Surgery Clinic of Malatya State Hospital for primary pilonidal sinus disease between January 2014 and December 2017 were evaluated retrospectively. Results: Female sex and family histories of pilonidal sinus disease and hypertrichosis were significantly higher in patients with than without hypertrichosis (p=0.030, p=0.035, p<0.001). The mean progesterone level was significantly lower in female patients with hypertrichosis than female patients without hypertrichosis (p=0.003).
Conclusion:Being overweight or obese, having an occupation that requires long-time sitting and having a family history predisposed to developing pilonidal sinus disease.