Sacral schwannoma with intraosseous extension

Silva, Carlos Dias; Mateus, José Eduardo; Silva, Joana Oliveira; Vaio, Teresa

doi:10.1136/bcr-2018-227095

Cited by 3 publications

(3 citation statements)

References 3 publications

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“…Male patients outnumber female patients (male 16, female 11) with patient ages ranging between 22 and 75 years. The majority of cases presented were in patients in their 40s 2–23…”

Section: Discussionmentioning

confidence: 99%

“…Recurrence is rare but may be associated with incomplete resection 3 25. All reported cases in the literature underwent surgical resection of the tumour,2–23 25 and while the length of follow-up varies, the vast majority of the cases were recurrence free. Only two cases had recurrence and required further surgery 11 15…”

Section: Discussionmentioning

confidence: 99%

“…This may be applicable to patients with minimal symptoms who have a confirmed histological diagnosis of schwannoma and who are NF2 negative. The vast majority of intraosseous schwannomas in the literature have been treated with surgical resection,2–23 with almost all of these lesions demonstrating benign histology. En bloc surgical intervention in this patient’s case would result in resection of the right L3 nerve root and potentially other elements of the lumbosacral plexus resulting in marked weakness in the right lower limb.…”

Section: Discussionmentioning

confidence: 99%

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Lumbar spinal intraosseous schwannoma: a non-operative approach

et al. 2022

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Intraosseous schwannomas are benign tumours composed of nerve sheath cells, most commonly affecting the mandible and sacrum. Such intraosseous schwannomas in the vertebra can result in spinal instability causing deformity, pain and even neurological compression. Vertebral involvement in the lumbar spine is extremely rare. A case of a schwannoma of the lumbar spine at the level of L3/L4 is presented. It resulted in progressive lower back pain and right lower limb radiculopathy. The clinical findings, radiological reports and histological diagnosis of this case, along with a review of the literature, are presented. The rationale for non-surgical management of this rare benign tumour is also explored.

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“…Male patients outnumber female patients (male 16, female 11) with patient ages ranging between 22 and 75 years. The majority of cases presented were in patients in their 40s 2–23…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Lumbar spinal intraosseous schwannoma: a non-operative approach

et al. 2022

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Surgical management of sacral schwannomas: a 21-year mayo clinic experience and comparative literature analysis

et al. 2022

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Introduction: Sacral and presacral schwannomas are rare and account for a minority of spinal schwannomas. We aim to present our institution's experience surgically treating sacral schwannomas over twenty-one years. Additionally, we assess the literature for surgical cases of sacral schwannomas to compare tumor characteristics and outcomes following resection.Methods: Data on demographics, presenting symptoms, lesion characteristics, surgical management, and outcomes were collected for 27 patients treated surgically for sacral or presacral schwannoma between 1997 and 2018 at all Mayo Clinic locations and compared to those of patients found in the literature.Results: We identi ed 31 studies in the literature containing 93 patients with sacral schwannoma treated surgically. Our patients and those in the literature experienced similar symptoms, with the most common symptom being pain and the least common being sexual dysfunction, and age at diagnosis. Most of our patients (59.3%) reported full recovery from preoperative symptoms, while a minority reported a partial recovery (33.3%) and no recovery (11.1%). A smaller percentage of patients found in the literature experienced full recovery (31.9%) and partial recovery (29.8%) but also no recovery (1.1%). Our patients experienced fewer complications (14.8% versus 25.5%). Conclusion:Outcomes of patients with sacral or presacral schwannomas vary based on patient demographics, tumor characteristics, symptoms, and surgical treatment. Among the range of symptoms experienced by these patients, the most common is pain. Prognosis improves and overall survival rate is high when the surgical approach towards sacral schwannomas is prepared and executed appropriately.

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Imaging Features of Intraosseous Schwannoma: A Case Series and Review of the Literature

et al. 2023

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To characterize the imaging features of patients with pathologically confirmed intraosseous schwannoma (IOS), institutional pathology and imaging databases were searched for IOS cases over a period of 17 years. A musculoskeletal radiologist evaluated all imaging studies. Additionally, a literature search was performed to identify IOS cases that had imaging findings of at least two modalities. Six patients (one female, five males, mean age of 50 ± 14 years) with IOS were identified, with all lesions localized to the lumbosacral region. Radiographic imaging was available in four patients, while all patients underwent CT and MR imaging. Radiographs depicted lytic lesions, and CT depicted heterogeneous expansile lesions with centrally hypodense areas and peripheral sclerosis. All cases involved extra-osseous extension, producing a mass effect on adjacent soft tissues and nerve roots. On MRI, the neoplasms displayed iso- to- slightly- low signal intensity on T1-weighted images and hyperintense signal intensity on T2-weighted images with heterogeneous enhancement. The literature review resulted in 102 IOS cases, which to the best of our knowledge, is the largest review on IOS, and the imaging findings of the previously published cases were the same as our cases. IOSs are rare benign neoplasms that should be considered in the differential diagnosis of well-defined expansile lytic lesions with sclerotic borders. This is particularly important in middle-aged adults with mandibular, sacral, or vertebral body mass.

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Sacral schwannoma with intraosseous extension

Cited by 3 publications

References 3 publications

Lumbar spinal intraosseous schwannoma: a non-operative approach

Lumbar spinal intraosseous schwannoma: a non-operative approach

Surgical management of sacral schwannomas: a 21-year mayo clinic experience and comparative literature analysis

Imaging Features of Intraosseous Schwannoma: A Case Series and Review of the Literature

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