Saccharomyces boulardii produces a soluble anti-inflammatory factor that inhibits NF-κB-mediated IL-8 gene expression

Sougioultzis, Stavros; Simeonidis, Simos; Bhaskar, K. Ramakrishnan; Chen, Xinhua; Anton, Pauline M.; Keates, Sarah; Pothoulakis, Charalabos; Kelly, Ciarán P.

doi:10.1016/j.bbrc.2006.02.080

Cited by 171 publications

(141 citation statements)

References 34 publications

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“…Some commensal bacteria secrete effector molecules that stimulate the host to provide a nutrient source, as well as inhibit the inflammatory response (Hooper andGordon, 2001a, 2001b;Sougioultzis et al, 2003).…”

Section: Adaptations Of the Commensal Microbiota To The Gut Environmentmentioning

confidence: 99%

The Gut Microbiota: Ecology and Function

Willing

Jansson

2014

The Fecal Bacteria

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Section: Adaptations Of the Commensal Microbiota To The Gut Environmentmentioning

confidence: 99%

The Gut Microbiota: Ecology and Function

Willing

Jansson

2014

The Fecal Bacteria

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“…The positive effect on the intestinal mucous layer, the proliferation of epithelial cells and mucosal macrophages observed in piglets (Bontempo et al, 2006) may also take place in young ruminants. Sougioultzis et al (2006) showed that S. boulardii produces a soluble anti-inflammatory factor that have beneficial effects on human intestinal epithelial cells and monocytes. Such effect could also be found in animal colonocytes and monocytes.…”

Section: Yeast Cells Yeast Cellsmentioning

confidence: 99%

Use of ‘natural’ products as alternatives to antibiotic feed additives in ruminant production

Jouany

Morgavi

2007

Animal

226

162

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The banning in 2006 of the use of antibiotics as animal growth promoters in the European Union has increased demand from producers for alternative feed additives that can be used to improve animal production. This review gives an overview of the most common non-antibiotic feed additives already being used or that could potentially be used in ruminant nutrition. Probiotics, dicarboxylic acids, enzymes and plant-derived products including saponins, tannins and essential oils are presented. The known modes of action and effects of these additives on feed digestion and more especially on rumen fermentations are described. Their utility and limitations in field conditions for modern ruminant production systems and their compliance with the current legislation are also discussed.

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“…This yeast is frequently prescribed in a lyophilized form as a biotherapeutic agent. Saccaromyces boulardii (S.boulardii) has been used in treatment of several intestinal diseases including IBS (5,21,28,29,45,49) .…”

Section: Introductionmentioning

confidence: 99%

Treatment of Diarrhea-Predominant Irritable Bowel Syndrome With Mesalazine and/or Saccharomyces Boulardii

Boiocchi

Almeida

Leite

et al. 2013

Arq. Gastroenterol.

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-Results -Compared to baseline, there were statistically significant reduction of symptom score after 30 th day therapy in all three groups: MG (P<0.0001); MSbG (P<0.0001) and in SbG (P = 0.003). There were statistically significant differences in the symptom score at 30 th day therapy of the MG, MSbG and SbG groups (P = 0.03). There were no statistical differences between MSbG and MG symptom score at 30th day therapy (P = 0.9). Conclusions -The use of mesalazine alone, Saccharomyces boulardii alone or combined treatment with mesalasine and Saccaromyces boulardii improved IBS-D symptoms. The improvement of the symptom score was greater with mesalazine alone or combined with Sb as compared with Sb treatment alone. These preliminary results suggest that mezalazine may be useful in treatment of IBS-d patients, and warrant further larger studies. HEADINGS -Irritable bowel syndrome. Diarrhea. Mesalamine. Saccharomyces boulardii.

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Saccharomyces boulardii produces a soluble anti-inflammatory factor that inhibits NF-κB-mediated IL-8 gene expression

Cited by 171 publications

References 34 publications

The Gut Microbiota: Ecology and Function

The Gut Microbiota: Ecology and Function

Use of ‘natural’ products as alternatives to antibiotic feed additives in ruminant production

Treatment of Diarrhea-Predominant Irritable Bowel Syndrome With Mesalazine and/or Saccharomyces Boulardii

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