SA16 Technology-Assisted Adaptive Recruitment Strategy for a National Study of Immunogenicity of COVID-19 Vaccines and Levels of Sars-COV-2 Neutralising Antibody in the Bruneian Population

Shim, CY; Ghani, Hazim; Ahmad, Liyana; Sharif, Hanisah; Alikhan, MF; Bagol, Saifuddien Haji; Taib, Surita; Tan, CW; Ong, XM; Lf, Wang; Han, GF; Xiao, Y; Y, Song; Wei, Yuan; Wong, Justin; Naing, Lin; Cunningham, AC

doi:10.1016/j.jval.2022.04.1682

Value in Health

2022

DOI: 10.1016/j.jval.2022.04.1682

|View full text |Cite

SA16 Technology-Assisted Adaptive Recruitment Strategy for a National Study of Immunogenicity of COVID-19 Vaccines and Levels of Sars-COV-2 Neutralising Antibody in the Bruneian Population

CY Shim¹,

Hazim Ghani

Liyana Ahmad

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2022

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The research team would like to acknowledge the hard work and enthusiastic support of the student volunteers and phlebotomists from the Ministry of Health, as well as the participants for their interests and donation of blood for this study. A poster of the manuscript's content was presented by CS virtually during the ISPOR 2022 conference ( 93 ).…”

mentioning

confidence: 99%

Technology-assisted adaptive recruitment strategy for a large nation-wide COVID-19 vaccine immunogenicity study in Brunei

Shim¹,

Chan²,

Wei³

et al. 2022

Front. Public Health

View full text Add to dashboard Cite

A national study was conducted in Brunei to assess and compare the immunogenicity of the various brands of COVID-19 vaccines administered to the population as part of the National COVID-19 Vaccination Programme. Most of the population have had received at least 2 doses of BBIBP-CorV, AZD1222 or MRNA-1273 vaccines. Neutralising antibodies against SARS-CoV-2 induced by these vaccines will be analysed to infer population-level immune protection against COVID-19. During the 5-week recruitment period, 24,260 eligible individuals were invited to the study via SMS, out of which 2,712 participants were enrolled into the study. This paper describes the novel adaptive strategy used to recruit the study participants. Digital technology was leveraged to perform targeted online recruitment to circumvent the limitations of traditional recruitment methods. Technology also enabled stratified random selection of these eligible individuals who were stratified based on age, gender and vaccine brand. Data was extracted from the electronic health records, the national mobile health application and a third-party survey platform and integrated into a dedicated research platform called EVYDResearch. The instant availability and access to up-to-date data on EVYDResearch enabled the study team to meet weekly and adopt an adaptive recruitment strategy informed by behavioural science, where interventions could be quickly implemented to improve response rates. Some examples of these include incorporating nudge messaging into SMS invitations, involving the Minister of Health to make press announcements on this study, media coverage, setting up an enquiries hotline and reaching out to foreign language speaking expatriates of a local multinational company to participate in this study. Data integration from various data sources, real time information sharing and a strong teamwork led to good outcomes adaptable to the progress of recruitment, compared to the more time-consuming and static traditional recruitment methods.

show abstract

mentioning

confidence: 99%

Technology-assisted adaptive recruitment strategy for a large nation-wide COVID-19 vaccine immunogenicity study in Brunei

Shim¹,

Chan²,

Wei³

et al. 2022

Front. Public Health

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

SA16 Technology-Assisted Adaptive Recruitment Strategy for a National Study of Immunogenicity of COVID-19 Vaccines and Levels of Sars-COV-2 Neutralising Antibody in the Bruneian Population

Cited by 1 publication

References 0 publications

Technology-assisted adaptive recruitment strategy for a large nation-wide COVID-19 vaccine immunogenicity study in Brunei

Technology-assisted adaptive recruitment strategy for a large nation-wide COVID-19 vaccine immunogenicity study in Brunei

Contact Info

Product

Resources

About