Sa1568 The Efficiency of Colonic Capsule Endoscopy in Detection of Colorectal Polyps and Cancers Compared to Colonoscopy - Final Results of Multicenter, Prospective, Cross-Over Study

Suchánek, Štěpán; Grega, Tomáš; Voska, Michal; Májek, Ondřej; Tachecí, Ilja; Benes, Marek; Drastich, Pavel; Vojtechova, Gabriela; Bunganič, Bohuš; Martínek, Jan; Bureš, Jan; Špičák, Julius; Zavoral, Miroslav

doi:10.1016/j.gie.2015.03.1357

Cited by 3 publications

(3 citation statements)

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“…In seven studies, one or more gastroenterologists or endoscopists were trained in reading CCE videos [15 -18, 20 -22]. Two studies only mentioned that the videos were reviewed by centers that specialized in capsule endoscopy [14,19]. One study used the services of Corporate Health, a company of nur-ses and physicians trained in CCE reading [11].…”

Section: Experience Of Colon Capsule Readersmentioning

confidence: 99%

Colon capsule endoscopy in colorectal cancer screening: a systematic review

et al. 2021

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Introduction Primary colonoscopy and fecal immunochemical test (FIT) are the most commonly used colorectal cancer (CRC) screening modalities. Colon capsule endoscopy (CCE) might be an alternative. Data on the performance of CCE as a CRC screening tool in a screening population remain scarce. This is the first systematic review to provide an overview of the applicability of CCE as a CRC screening tool. Methods A systematic search was conducted of literature published up to September 2020. Studies reporting on CRC screening by second-generation CCE in an average-risk screening population were included. Results 582 studies were identified and 13 were included, comprising 2485 patients. Eight studies used CCE as a filter test after a positive FIT result and five studies used CCE for primary screening. The polyp detection rate of CCE was 24 % – 74 %. For polyps > 6 mm, sensitivity of CCE was 79 % – 96 % and specificity was 66 % – 97 %. For polyps ≥ 10 mm, sensitivity of CCE was 84 % – 97 %, which was superior to computed tomographic colonography (CTC). The CRC detection rate for completed CCEs was 93 % (25/27). Bowel preparation was adequate in 70 % – 92 % of examinations, and completion rates varied from 57 % to 92 %, depending on the booster used. No CCE-related complications were described. Conclusion CCE appeared to be a safe and effective tool for the detection of CRC and polyps in a screening setting. Accuracy was comparable to colonoscopy and superior to CTC, making CCE a good alternative to colonoscopy in CRC screening programs, although completion rates require improvement.

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Section: Experience Of Colon Capsule Readersmentioning

confidence: 99%

Colon capsule endoscopy in colorectal cancer screening: a systematic review

et al. 2021

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“…This study revealed that the sensitivity of CCE in detecting advanced CRC was 85% (95% CI: 62–97%) in a per‐patient analysis and 81% (95% CI: 58–95%) in a per‐lesion analysis. Previous studies have reported that the sensitivities of CCE in detecting CRC were 75–100% . However, these were limited somewhat by the small sample numbers of CRC patients (fewer than five patients).…”

Section: Discussionmentioning

confidence: 99%

“…Although advanced CRC is clinically more significant than are polyps, studies of the efficacy of CCE in terms of CRC detection are few in number. Several studies have reported that the sensitivities of CCE in detecting CRC were 75–100% . However, these have been restricted somewhat by the small sample numbers of CRC patients.…”

Section: Introductionmentioning

confidence: 99%