Sa1247 EARLY DIAGNOSIS IS ASSOCIATED WITH IMPROVED CLINICAL OUTCOME IN BENIGN ESOPHAGEAL PERFORATIONS: AN INDIVIDUAL PATIENT DATA META-ANALYSIS

Vermeulen, Bram D.; Leeden, Britt van der; Rosman, Camiel; Siersema, Peter D.

doi:10.1016/j.gie.2019.03.137

Cited by 1 publication

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Boerhaave syndrome is a life-threatening condition that has a high mortality rate even with prompt diagnosis and rapid intervention. A "pooled meta-analysis published in 2013 showed a mortality rate of 12%, while a nation-wide population-based study in England reported a 35% overall mortality rate in patients" with Boerhaave syndrome [4]. Boerhaave is caused by increased intraesophageal pressure leading to a transmural tear through the esophagus.…”

Section: Discussionmentioning

confidence: 99%

“…While vomiting is the most common cause of the esophageal rupture, other etiologies include weightlifting, defecation, seizures, trauma, and other events that trigger an increase in intrathoracic pressure must be sought. Individuals with excessive alcohol and excessive food intake are also at an increased risk [4]. These patients may present with vague symptoms or some combination of the classic Mackler triad: vomiting, chest pain, and subcutaneous emphysema.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Atypical Presentation of Boerhaave Syndrome With Hypoxia and Unresponsiveness

Bury¹,

Fratczak²,

Nielson³

2022

Cureus

View full text Add to dashboard Cite

The following case discusses the atypical presentation of a spontaneous esophageal rupture that presented as acute hypoxic respiratory failure in the emergency department. The patient initially arrived by ambulance with a chief complaint of non-radiating chest pain for approximately one hour. Within minutes after arrival, the patient became hypoxic and bradycardic, requiring supplemental oxygen. A computed tomography (CT) angiogram of the chest showed a pneumothorax, pneumomediastinum, and left lower lobe consolidations concerning for pneumonia. The patient was resuscitated in the emergency department, and a chest tube thoracostomy was performed. Upon admission to the hospital, an esophagogram with contrast showed an esophageal leak at the gastroesophageal junction with the contrast extending into the left pleural space which required surgical intervention. This case highlights the complicated nature and variable presentations of Boerhaave syndrome and the importance of stabilizing the airway, breathing, and circulation in a decompensating patient even when the etiology is not clear at the time of presentation.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%