S95 Relationship between obesity and prostate cancer at the time of biopsy

Drenidis, G.; Papazoglou, J.; Savidis, D.; Diamantis, G.; Sakelariou, G.; Leontis, S.; Rempelakos, A.

doi:10.1016/s1569-9056(09)74976-0

Cited by 1 publication

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“…Obesity is an increasing global epidemic, with implications in the treatment of prostate cancer. Obese men have significantly greater chance of dying of prostate cancer than non‐obese men, and are approximately twice as likely to develop a high‐grade prostate cancer . Obesity is associated with a 98% increase in prostate cancer risk, after adjusting for lower prostate‐specific antigen (PSA) and a larger prostate size .…”

Section: Introductionmentioning

confidence: 99%

“…Obese men have significantly greater chance of dying of prostate cancer than non-obese men, 3 and are approximately twice as likely to develop a high-grade prostate cancer. 4 Obesity is associated with a 98% increase in prostate cancer risk, after adjusting for lower prostate-specific antigen (PSA) and a larger prostate size. 5 In addition, overweight or obese prostate cancer patients are more likely to be younger and have co-morbidities such as hypertension and diabetes.…”

Section: Introductionmentioning

confidence: 99%

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Obesity does not influence prostate intrafractional motion

Brown

Tan

Cooper

et al. 2018

J of Medical Radiation Sci

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IntroductionMotion of the prostate is problematic in the accurate delivery of external beam radiation therapy (EBRT) for prostate cancer. This study investigated the relationship between body mass index (BMI), an easily measured indicator of obesity, and prostate motion.MethodsProstate motion during EBRT was assessed by measuring the displacement of fiducial markers implanted within the prostate in 130 prostate cancer patients. Interfractional motion was corrected on daily imaging through pre‐treatment cone‐beam‐computed tomography (CBCT) and intrafractional motion measured using movie sequences captured using an electronic portal imaging device (EPID) during treatment delivery.ResultsThere was no statistically significant relationship between the mean intrafractional motion and BMI, except in the left‐right (LR) translation (P = 0.049) over the study population. For each BMI category, there was no statistical significance (P > 0.05) between any of the translations/rotations except LR (P = 0.003).ConclusionWhile intrafractional motion is an important consideration, prostate motion cannot be reliably predicted through measurement of patient's BMI.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%