S75. Suicide: Out of Time?

Lethal Suicide Attempt After Dextromethorphan-Associated Sleep Terror

“…Mr J's remote history of vivid dreams is particularly relevant given the appearance of a sleep terror-like event the night before the stabbing, when taking dextromethorphan (75 mg/d) within the recommended daily dose, and the severity of the parasomnia, ultimately leading to a highly lethal suicide attempt. Because of its binding to multiple receptors, dextromethorphan can induce varied symptoms, including euphoria, dissociation, slurred speech, ataxia, nystagmus, and psychosis when used above recommended doses 1,3 . Noteworthy, Mr J did not exhibit any psychotic or mood symptoms.…”