S2579 TB or Not TB: Tuberculous Peritonitis in a Patient With Decompensated Cirrhosis

Khalid, Sameeha; Ahsan, Shangida; Roytman, Marina

doi:10.14309/01.ajg.0000783848.19360.19

Am J Gastroenterol

2021

DOI: 10.14309/01.ajg.0000783848.19360.19

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S2579 TB or Not TB: Tuberculous Peritonitis in a Patient With Decompensated Cirrhosis

Sameeha Khalid

Shangida Ahsan

Marina Roytman

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Ciclosporin/linezolid

2021

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Ciclosporin/linezolidThrombocytopenia and maculopapular rash: case report A 39-year-old man developed thrombocytopenia during antibiotic therapy with linezolid for tuberculous peritonitis. Additionally, he developed maculopapular rash during treatment with ciclosporin for tuberculous peritonitis [routes, dosages, durations of treatment to reaction onset and reaction outcomes not stated].The man had a history of history of alcohol abuse. He was admitted to a hospital after experiencing malaise and weight loss for 2 months. Based on his findings there was a suspicion of bacterial peritonitis, for which he started receiving empirical therapy with ceftriaxone. He also found to have liver cirrhosis. Due to recurrent ascites and fevers without improvement, his antibiotic therapy was broadened by including linezolid, isoniazid, ethambutol and levofloxacin, which resulted in resolution of his fevers. Subsequently, he was diagnosed with tuberculous peritonitis secondary to Mycobacterium Tuberculosis infection. His course was complicated by thrombocytopenia, which was thought to be caused by linezolid.Linezolid was stopped and the man started receiving ciclosporin [cyclosporine]. However, he developed diffuse maculopapular rash, which was possibly related to ciclopsorin. Therefore, ciclosporin was switched to amikacin. He showed clinical improvement after treatment and was discharged with antitubercular treatment.

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Ciclosporin/linezolid

2021

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S2579 TB or Not TB: Tuberculous Peritonitis in a Patient With Decompensated Cirrhosis

Cited by 1 publication

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Ciclosporin/linezolid

Ciclosporin/linezolid

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