Abstract:BackgroundThe rs3800779 polymorphism at KCNH2 gene, which encodes for a Voltage-Gated Potassium Channel Subunit, has been associated with the risk for schizophrenia (SZ) and with changes in the expression of a brain isoform with specific electrophysiological characteristics (Huffaker et al., 2009). It has been hypothesized that the KCNH2 gene variability could be involved in SZ by means of modulating the neuronal excitability. Graph-theory parameters applied to electroencephalographic (EEG) activity are useful… Show more
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