Abstract:Introduction and objectivesProgressive respiratory disease accounts for most of the mortality and morbidity in CF. Identification of early lung disease is imperative to recognise young patients who are at high risk of developing future lung damage. The London CF collaboration has shown that infant pulmonary function at one and at two years is essentially normal, and one year HRCT has mild abnormalities only, so new markers need to be identified. We have used ventilation scans (VS) at the CF annual assessment i… Show more
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