S1025 Prevalence of Osteoporosis Among Patients With Inflammatory Bowel Diseases: A Retrospective Cohort Study

Abstract

Introduction: IBD patients are at increased risk for loss of bone mass due to diverse factors such as steroid treatment, chronic inflammation, and malabsorption. Guidelines recommend screening IBD patients with high steroid use, and recurrent or persistently active disease for osteoporosis with a DXA scan. We evaluated the prevalence, and characteristics of osteoporosis in a nationwide cohort of IBD patients. Methods: This is a retrospective cohort study. We collected data from the Healthcare Cost and Utilization Project (HCUP) Nationwide Readmission Databases (NRD) 2016-2018. Median and IQR were used to describe Continuous variables, and proportions were used with categorical variables. Comparison between groups was performed by Mann Whitney test for continuous variables and the Chi-Square test for Categorical variables. Results: We analyzed 365,152 index hospital discharges with IBD. Of whom, 15,726 (4.3%) had osteoporosis and 4,375 (1.2%) had Osteopenia. Of those with osteoporosis, 95.1% had osteoporosis without pathological fracture while 4.9% had osteoporosis with a pathological fracture. The majority of IBD patients with osteoporosis were females (80.5%). IBD patients with osteoporosis were older (median age: 71;