S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis
Hermine I Brunner,
Grant S Schulert,
Alyssa Sproles
et al.
Abstract:Background
Juvenile idiopathic arthritis (JIA) comprises a heterogeneous group of conditions that can cause marked disability and diminished quality of life. Data on predictors of clinical response are insufficient to guide selection of the appropriate biologic agent for individual patients. This study aimed to investigate the propensity of S100A8/9 and S100A12 as predictive biomarkers of abatacept response in polyarticular-course juvenile idiopathic arthritis (pJIA).
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