S1 guideline: Differential diagnosis of acute and chronic redness of the lower legs

Abstract

Acute or chronic redness of the lower leg is a frequent reason for visits to clinics and practices. The differential diagnosis is often challenging. The aim of this guideline is to define criteria and procedures for the differential diagnosis of acute or chronic, unilateral or bilateral redness of the lower leg. Finding the correct diagnosis is essential for selecting an appropriate treatment and can help to reduce the inappropriate use of antibiotics. The guideline committee identified the most relevant differential diagnoses: 1. erysipelas, 2. stasis dermatitis, 3. hyperergic ictus reaction, 4. superficial and deep vein thrombosis, 5. gout, 6. chronic allergic contact dermatitis, and 7. acute toxic or allergic contact dermatitis. Algorithms/diagnostic pathways, each of which can be broken down into anamnesis, clinical examination, and diagnostics, have been developed for these seven diagnoses. In addition, the guideline group identified over 40 other relevant diagnoses and summarized their characteristics in a table to facilitate further differential diagnoses.

Global Guidelines in Dermatology Mapping Project (GUIDEMAP)—A systematic review of the methodological quality of contact dermatitis clinical practice guidelines

“…Of these 25 reports, 11 were identified as duplicate publications, and one publication focused on implementation rather than being a CPG, and were therefore excluded. [35][36][37][38][39][40][41][42][43][44][45][46] The manual search yielded 13 additional reports, one 47 of which did not meet the explicit criteria of a guideline. In total we identified 25 CPGs that met the inclusion criteria (see Figure 1).…”

“…Full‐text copies of the remaining 25 records were obtained for further evaluation. Of these 25 reports, 11 were identified as duplicate publications, and one publication focused on implementation rather than being a CPG, and were therefore excluded 35–46 . The manual search yielded 13 additional reports, one 47 of which did not meet the explicit criteria of a guideline.…”