2017
DOI: 10.1111/anec.12516
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S‐R difference in V1‐V2 is a novel criterion for differentiating the left from right ventricular outflow tract arrhythmias

Abstract: S-R difference in V1-V2 is a novel and simple electrocardiographic criterion for accurately differentiating RVOT from LVOT sites of ventricular arrhythmia origins. The use of this simple ECG measurement could improve the accuracy of OTVA localization, could be beneficial for decreasing ablation duration and radiation exposure. Further studies with larger patient population are needed to verify the results of this study.

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Cited by 20 publications
(21 citation statements)
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References 23 publications
(36 reference statements)
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“…Kaypakli et al proposed the S-R difference in leads V1 and V2 (V1–2 SRd), calculated using this formula on the 12-lead surface ECG: (V1S amplitude + V2S amplitude) – (V1R amplitude + V2R amplitude). [ 22 ] Owing to its anterior position, the RVOT is closer to leads V1 and V2 than the LVOT, and therefore RVOT VAs will produce a deeper S wave and smaller R wave in these leads; conversely, the LVOT is further from leads V1 and V2 relative to the RVOT, and therefore LVOT VAs will give rise to a higher R wave and smaller S wave in these leads. Thus, V1-2 SRd is lower in LVOT sites of origin than in RVOT sites of origin, and the cut-off proposed by Kaypakli et al is 1.625 mV (sensitivity, 95.1%; specificity, 85.5%).…”
Section: Current Ecg Criteria For Differentiating Lvot From Rvot Originmentioning
confidence: 99%
“…Kaypakli et al proposed the S-R difference in leads V1 and V2 (V1–2 SRd), calculated using this formula on the 12-lead surface ECG: (V1S amplitude + V2S amplitude) – (V1R amplitude + V2R amplitude). [ 22 ] Owing to its anterior position, the RVOT is closer to leads V1 and V2 than the LVOT, and therefore RVOT VAs will produce a deeper S wave and smaller R wave in these leads; conversely, the LVOT is further from leads V1 and V2 relative to the RVOT, and therefore LVOT VAs will give rise to a higher R wave and smaller S wave in these leads. Thus, V1-2 SRd is lower in LVOT sites of origin than in RVOT sites of origin, and the cut-off proposed by Kaypakli et al is 1.625 mV (sensitivity, 95.1%; specificity, 85.5%).…”
Section: Current Ecg Criteria For Differentiating Lvot From Rvot Originmentioning
confidence: 99%
“…So it is challenging to recognize the origin of the PVCs. Different ECG algorithms have been proposed for differentiation of left and right sided PVCs (7)(8)(9)(10)(11)(12). Their accuracy and usefulness remain limited especially when the transition in the precordial leads occurs in V3 (10).…”
Section: Discussionmentioning
confidence: 99%
“…In these patients, a 3.5-mm irrigated-tip catheter (NaviStar, Biosense Webster) was used for mapping and ablation. Target ablation sites were chosen with the combination of activation mapping and pace mapping as described previously (12). If radiofrequency application was successful, it was maintained for 60 seconds in RVOT and for 30-45 seconds in aortic root.…”
Section: Ablation Protocolmentioning
confidence: 99%
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“…Several ECG methods have been proposed for distinguishing RVOT from LVOT [4,[10][11][12][13][14][15][16][17]. However, the accuracy and effectiveness of these algorithms have some shortcomings, which may account for the heterogenous QRS morphology of OT-VAs.…”
Section: Introductionmentioning
confidence: 99%