“…Spiperone,spiroxatrine,propranolol,pindolol,BMY 7378,NAN 190, and (S)-UH 301 are partial antagonists (Fozard and Kilbinger, 1985;Glennon et al, 1988;Hillver et al, 1990;Nelson and Taylor, 1986;Tricklebank et al, 1984;Yocca et al, 1987). (S)-UH-301 displays 5-HT 1A receptor antagonist properties, but has only eightfold selectivity for 5-HT 1A relative to dopamine D2 binding sites (Hillver et al, 1990). Another compound, (1,1,3-trioxo-2H-1,2-benzoisothiazol-2-yl)butyl]-1-piperazinyl6 1H-indole-2-carboxylate), has been described as a potent and selective 5-HT 1A receptor antagonist in vitro and in vivo (Schoeffter et al, 1993).…”