Ryggfrakturer og svangerskaps- og laktasjonsassosiert osteoporose

Rafey, Shima; Hübschle, Lars Michael; Bjørnerem, Åshild; Borgen, Tove Tveitan

doi:10.4045/tidsskr.19.0073

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…Strong loss of bone mass in the vertebral bodies can cause collapse and compressive fractures with strong back pain [13]. Vertebral fractures occur most commonly in PLO and are often multiple [14].…”

Section: Discussionmentioning

confidence: 99%

Pregnancy- and lactation-associated osteoporosis with vertebral fractures

Bozovic¹,

Elek²,

Jovanović³

et al. 2021

Srp Arh Celok Lek

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Introduction. Pregnancy- and lactation- associated osteoporosis (PLO) is a rare disease for which the pathophysiological mechanism is as yet incompletely known. The incidence of PLO is 0.4 in 100,000 women. It is considered that the number of undiagnosed patients is even higher. PLO can lead to multiple fragility compression fractures in the spinal vertebrae. Case outline. We present the case of a 30 years old woman (first-born, breastfeeding child) who comes for examination due to lower back pain that occurs after childbirth without any apparent cause. The patient was found to have low levels of vitamin D and low bone mineral density on osteodensitometry (established osteoporosis). Magnetic resonance imaging (MRI) examination showed vertebral bodies fractures Th11, Th12 and L4. In therapy we used Vitamin D (800 iu/24 h), Alendronate (70 mg once weekly), calcium 1000 mg/24h and Thoracic Lumbar Sacral Orthosis (TLSO) as support to spine. After 12 months of treatment osteodensitometry findings were close to normal, control MRI showed no further collapse of vertebral bodies and clinical examination of spine was orderly. Conclusion. PLO is a rare clinical condition and it must be kept in mind in the differential diagnosis in patients having low back pain during or after pregnancy. Early diagnosis and treatment of PLO and regular follow-up of these cases are particularly important. The stability of the spine in patients with vertebral fractures must be carefully monitored as well as using the TLSO as a support for the spine.

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Section: Discussionmentioning

confidence: 99%

Pregnancy- and lactation-associated osteoporosis with vertebral fractures

Bozovic¹,

Elek²,

Jovanović³

et al. 2021

Srp Arh Celok Lek

View full text Add to dashboard Cite

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Pregnancy- and Lactation-Associated Osteoporotic Vertebral Fracture: A Case Report

Jadhav¹,

Jadhav²,

Varma³

2022

Cureus

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The report details an instance of a 29-year-old postpartum female who presented to us after six months of delivery and had symptoms of severe back pain since the sixth month of pregnancy. The pain was located in the lower thoracic and lumbar regions. It got aggravated by standing or walking and got relieved by lying down. The pain was radiating from the back to both lower limbs. On examination, forward rounding of the upper back, i.e., kyphosis, was seen, for which the patient was advised to get an X-ray, which was suggestive of severe osteopenia with wedging of L1-L4 vertebrae. For a thorough assessment, MRI was performed, which confirmed exaggerated kyphosis at L1 and L2 with mild scoliosis in the thoracolumbar region. The patient was advised to take calcium and vitamin D supplements with bisphosphonates. A monthly checkup was advised. After four months, the symptoms of the patient were partially eased. On investigation, the serum calcium and phosphorous levels were found to be within the normal range.

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Ryggfrakturer og svangerskaps- og laktasjonsassosiert osteoporose

Cited by 2 publications

References 6 publications

Pregnancy- and lactation-associated osteoporosis with vertebral fractures

Pregnancy- and lactation-associated osteoporosis with vertebral fractures

Pregnancy- and Lactation-Associated Osteoporotic Vertebral Fracture: A Case Report

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