Ruthenium carboranyl complexes with 2,2′-bipyridine derivatives for potential bimodal therapy application

Abstract

The substituents at the bipyridine lead to different cell uptake and stability.

Synthesis of Novel Pseudocloso Ruthenacarboranes based on an Unsubstituted nido‐C2B9H112− Ligand

“…The typical values for C c H 1 H chemical shift for closo ruthenacarboranes lie in the range from 1.5 to 3.5 ppm depending on auxiliary ligands. [19][20][21][22][23][24][25][26][27][28] At the same time the signals of protons of complexes 2-4 and 6 lie in the lower field area. The data provided in the Table 2 shows that the increase of the donating ability of alkyl substituent in complexes 3, 4, 6 (methyl, ethyl, tert.-butyl) results in a shielding of the C c À H resonances.…”

X-ray sensitive selenium-containing Ru complexes sensitize nasopharyngeal carcinoma cells for radio/chemotherapy

“…30 Then, an Ru complex is highly specific for mitochondria, where the Ru complex leads to the excessive generation of ROS, causing activation of the endogenous apoptosis of cancer cells via an endoplasmic reticulum stress signal pathway. [31][32][33][34] However, they still have problems such as a lack of selectivity and poor antitumor activity. Therefore, it is necessary to improve their structure.…”

Remote Effect from Boron Cluster: Tunable Photophysical Properties of o‐Carborane‐Based Luminogens

“…As an electronic acceptor with a three‐dimensional cage structure, o ‐carborane also has been used as an excellent building block in organic luminogens [24] . Usually, the o ‐carboranyl group is directly connected with a chromophore like carbazole to form o ‐carborane‐based luminogens (Scheme 1a and Figure S1) [25–48] . Such a carboranyl appended π‐conjugation possesses D‐A [35] or D‐π‐A [28] molecular geometry and displays intriguing and tunable photophysical properties, such as AIE, room‐temperature phosphorescence and mechanochromic luminescence [45] .…”