Ruptured gastro-intestinal stromal tumor as a surgical emergency: A case report and literature review

Abstract

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs of the small bowel are rare, and often present with an abdominal mass and/or bleeding. Chemotherapy and surgery are the mainstay of therapy. Here, we discuss an unusual case of a ruptured jejunal GIST with hemoperitoneum and recurrence despite surgical excision followed by Imatinib treatment. Forty-five cases of ruptured small intestinal GISTs were identified in the literature. Most cases were in males and were found to be at the site of the jejunum.

Surgical management of a locally advanced jejunal stromal tumor: A case report of a challenging condition

“…These side effects will adversely affect the patient's short and long-term prognosis [ 10 ]. In addition, before prescribing imatinib in the neoadjuvant course for 6 to 12 months, the risks of major complications related to spontaneous evolution of the jejunal GIST (rupture, perforation, and hemorrhage) must be considered [ [11] , [12] , [13] ]. Finally, whereas locally advanced jejunal GISTs have shown similarities with their analogs in the stomach, clinical evolution appears to be less favorable [ 14 , 15 ].…”