Ruptured Corpus Luteum with Hemoperitoneum: Case Characteristics and Demographic Changes Over Time

Abstract

The manifestations of corpus luteum hemorrhage in this study were similar to those observed in the 1980s at the same medical center. However, the demographic parameters (age, marital status) and the modalities of treatment (conservative treatment, mode of surgical interventions) had changed in line with the evolution of society, culture, and the progress of medical science over the past 20 years.

Massive hemoperitoneum from a ruptured corpus luteum cyst masquerading as biliary colic

“…More recent case reports of massive hemoperitoneum from a ruptured corpus luteum cyst are associated with systemic anticoagulation, coagulation disorders, von Willebrand disease, and sickle cell anemia [6][7][8][9]. Symptoms presenting following sexual intercourse, such as those described by our patient, are also described in literature [10,11]. It is possible that the changes in intraluminal pressure created during sexual intercourse was a catalyst for cyst rupture.…”

Haemoperitoneum due to ruptured corpus luteum! managed conservatively-2 case reports and review of literature

“…A conservative approach is reported in a few case reports of late. 6,8,11,12,14 In either case the treatment targets at preserving ovarian function as well as at eliminating the source of bleeding. The products that can be used to restore haemostatic parameters and to stop hemorrhage in the case of critical bleeding due to warfarin include Plasma Cell Concentrate (PCC), FFP, and vitamin K. When the patient is haemodynamically stable (systolic BP >90 mmHg) with hemoglobin values that keep being constant over 4-6 hours of monitoring, a conservative approach can be tried if diagnosis of corpus luteal hemorrhage is certain.…”

“…PCC cost less than rFVIIa, effect is immediate, volume of infusion is small and therefore there is no fluid overload, they are considered the treatment of choice for rapid reversal of oral anticoagulation. 6,8,10,13,14 However, PCC are not available in India. Consideration is also given to inhibiting ovulation in future and preventing ovulation bleed by use of OCP or progestins.…”

Anticoagulant Induced Life Threatening Corpus Luteal Cyst Haemorrhage

“…In these people it may be fatal in 3% -11%. 3 Most often cyst rupture may occur between 20 th -26 th day of menstrual cycle. The severity of the patient's signs and symptoms with corpus luteum haemorrhage depends upon the extent of bleeding and the dose of anti-coagulants they are using, 4 regular monitoring with PT/INR may reduce this incidence.…”