Rupture of an intrahepatic aneurysm due to polyarteritis nodosa

Glassman, Ephraim; Skerrett, Philip V.

doi:10.1016/0002-9343(60)90230-8

Cited by 14 publications

(2 citation statements)

References 2 publications

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“…However, reports on such patients incidentally record that 3 were receiving treatment for rheumatoid arthritis (Weaver et al, 1968). 1 for Hashimoto's thyroiditis (Weaver et al, 1968), 1 for thyrotoxic goitre (Zeppa and Womack, 1963), and 5 for polyarteritis (Glassman and Skerrett, 1960). Autoaggressive disorders appear to account for some 15 % of reported intrahepatic artery aneurysms.…”

Section: Discussionmentioning

confidence: 99%

Ruptured hepatic aneurysm in systemic lupus erythematosus.

McCollum¹,

Sloan²,

Davison³

et al. 1979

Annals of the Rheumatic Diseases

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SUMMARY We report on a patient with systemic lupus erythematosus (SLE) who suffered catastrophic haemorrhage following rupture of an intrahepatic aneurysm. The association between hepatic artery aneurysm and SLE has not been recorded previously, but we have found evidence from the literature that there may be an association between autoaggressive disorders and this surgical emergency.Aneurysm of the hepatic artery is not common. When intrahepatic, it is associated with systemic disorders. In this report we describe a patient with systemic lupus erythematosus in whom rupture of an intrahepatic artery aneurysm occurred and led to ife-threatening haemorrhage.Case report An Asian women of 33 presented in 1965 with arthritis and joint swelling. She was anaemic and pyrexial with thinning head hair and pubic hair. A diagnosis of systemic lupus erythematosus (SLE) was made on the basis of marked anaemia, thrombocytopenia, a raised erythrocyte sedimentation rate, raised plasma gammaglobulins, and a positive LE cell preparation. The patient responded to treatment with 6-mercaptopurine and betamethasone.Ten years later she was admitted to hospital with arthralgia, pleuritic chest pain, and dependent oedema. X-rays showed bilateral pleural effusions, and an electrocardiogram suggested pericarditis. Further investigations showed antinuclear antibody (positive to 1/50) and raised DNA binding, confirming the diagnosis of SLE. Renal involvement produced proteinuria and diminished function (creatinine clearance 34 ml/min). Frusemide 120 mg with dexamethasone 4 mg was prescribed daily.

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Section: Discussionmentioning

confidence: 99%

Ruptured hepatic aneurysm in systemic lupus erythematosus.

McCollum¹,

Sloan²,

Davison³

et al. 1979

Annals of the Rheumatic Diseases

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“…Die Panarteriitis nodosa (PAN) ist als systemisch nekrotisierende Vasculitis mit multiplen Aneurysmen kleiner und mittelgroûer Arterien vergesellschaftet [13]; auch multiple hepatische Aneurysmen wurden vereinzelt beschrieben [2,3,5,8], jedoch regelmäûig in Assoziation mit Aneurysmen anderer Lokalisation (A. renalis, Aa. coronariae).…”

Section: Kasuistikunclassified

Abdominal bleeding in the presence of multiple intrahepatic aneurysms

Husmann

Hierholzer

Langrehr

2001

Chirurg

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A 17-year-old male patient presented with diffuse abdominal pain, acute drop in hemoglobin and free subhepatic fluid. The patient was transferred to our unit for investigation of presumed spontaneous hepatic bleeding. Questioning revealed daily medication of 2 g acetylsalicylic acid because of influenzal infection. At exploratory laparoscopy 1.8 l hematoma was removed; the origin of bleeding could not be identified. The liver surface appeared macroscopically unremarkable, with the exception of an aneurysmal dilatation of the cystic artery that was considered as possible bleeding cause. Postoperative angiography confirmed the presence of multiple aneurysmal dialatations of both left and right hepatic arteries. Extensive investigations did not show any further aneurysms or vascular abnormalities in any other part of the body. There was no evidence of a preexistent systemic vasculitis or primary collagen disease.

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Successful Surgical Treatment of Massive Abdominal Hemorrhage Due to Periarteritis Nodosa

Woods¹

1968

Arch Surg

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Rupture of an intrahepatic aneurysm due to polyarteritis nodosa

Cited by 14 publications

References 2 publications

Ruptured hepatic aneurysm in systemic lupus erythematosus.

Ruptured hepatic aneurysm in systemic lupus erythematosus.

Abdominal bleeding in the presence of multiple intrahepatic aneurysms

Successful Surgical Treatment of Massive Abdominal Hemorrhage Due to Periarteritis Nodosa

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