Rupture des membranes : physiopathologie, diagnostic, conséquences et prise en charge

Blanchon, Loı̈c; Accoceberry, M.; Belville, Corinne; Delabaere, Amélie; Prat, Cécile; Lémery, D.; Sapin, Vincent; Gallot, Denis

doi:10.1016/j.jgyn.2012.12.012

Cited by 10 publications

(2 citation statements)

References 109 publications

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“…pPROM affects 2-4% of singleton pregnancies and 7-20% of twin pregnancies [16]. This complication is responsible for one-third of preterm births (PTB) and is associated with an elevation of perinatal and maternal mortality [16,38,39]. Indeed, pPROM increases the risk of placental abruption, postpartum endometritis and chorioamnionitis [40,41].…”

Section: Definition and Consequences Of The Pprommentioning

confidence: 99%

Pathophysiological Implication of Pattern Recognition Receptors in Fetal Membranes Rupture: RAGE and NLRP Inflammasome

et al. 2021

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Preterm prelabor ruptures of fetal membranes (pPROM) are a pregnancy complication responsible for 30% of all preterm births. This pathology currently appears more as a consequence of early and uncontrolled process runaway activation, which is usually implicated in the physiologic rupture at term: inflammation. This phenomenon can be septic but also sterile. In this latter case, the inflammation depends on some specific molecules called “alarmins” or “damage-associated molecular patterns” (DAMPs) that are recognized by pattern recognition receptors (PRRs), leading to a microbial-free inflammatory response. Recent data clarify how this activation works and which receptor translates this inflammatory signaling into fetal membranes (FM) to manage a successful rupture after 37 weeks of gestation. In this context, this review focused on two PRRs: the receptor for advanced glycation end-products (RAGE) and the NLRP7 inflammasome.

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Section: Definition and Consequences Of The Pprommentioning

confidence: 99%

Pathophysiological Implication of Pattern Recognition Receptors in Fetal Membranes Rupture: RAGE and NLRP Inflammasome

et al. 2021

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“…Before 34SA, treatment is conservative with in utero transfer, antibiotic prophylaxis and corticosteroid therapy. 10 In most cases, the RPM will precede the start of spontaneous work within 24 hours by a few hours or days. However, it is an infectious risk factor, especially for chorioamniotitis and neonatal infections.…”

mentioning

confidence: 99%

Effect of premature rupture of membranes on the maternal and fetal prognosis during childbirth at the gynecology-obstetrics department of the Matam Communal Medical Center, Conakry, Guinea

Conté¹,

Alpha²,

Hawa³

et al. 2020

Int J Reprod Contracept Obstet Gynecol

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Background: Premature rupture of membranes (RPM) is defined by rupture of the amnion and chorion before entering labor within 24 hours leading to vaginal discharge of amniotic fluid without uterine contractions. Objective of this study was to improving the management of premature Ruptures of the membranes received in the service.Methods: This was a descriptive and analytical prospective study lasting six months from January 1 to June 30 2016.Results: During the study period, we collected 108 cases of RPM out of 1543 deliveries, representing a hospital frequency of 7%. RPM had more frequently concerned pregnant women aged 25-29 (37.04%), housewife (37.03%), primiparous (45.37%) and referral (52.78%). 95.37% were single pregnancies with cephalic presentation (80%) received between 37-42 weeks (84.26%). Management mainly consisted of antibiotic prophylaxis (100%), fetal pulmonary maturation and childbirth. The vagina was the main mode of delivery (62.04%). The maternal prognosis was dominated by chorioamnionitis (12.96%). The fetal one was made up of respiratory distress (40.71%) and prematurity (12.39%).Conclusions: RPM is frequent at the Matam municipal medical center. It is essential for its prevention to ensure health education of the population in general and genital hygiene in particular, to make a coherent prenatal follow-up while putting a particular accent on the detection and the treatment of genital infections.

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All-trans retinoic acid promotes wound healing of primary amniocytes through the induction of LOXL4, a member of the lysyl oxidase family

Rouzaire

Belville

Bouvier

et al. 2016

The International Journal of Biochemistry & Cell Biology

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Rupture des membranes : physiopathologie, diagnostic, conséquences et prise en charge

Cited by 10 publications

References 109 publications

Pathophysiological Implication of Pattern Recognition Receptors in Fetal Membranes Rupture: RAGE and NLRP Inflammasome

Pathophysiological Implication of Pattern Recognition Receptors in Fetal Membranes Rupture: RAGE and NLRP Inflammasome

Effect of premature rupture of membranes on the maternal and fetal prognosis during childbirth at the gynecology-obstetrics department of the Matam Communal Medical Center, Conakry, Guinea

All-trans retinoic acid promotes wound healing of primary amniocytes through the induction of LOXL4, a member of the lysyl oxidase family

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