Rupioid psoriasis on the hands

Rupioid Psoriasis

“…1 Contemporary analogies compare the concentric cone-like scale of rupioid psoriasis with the shells of limpets. 2 Differential diagnoses that may mani-fest with skin lesions of similar morphology include secondary syphilis, hyperkeratotic scabies, HIV, reactive arthritis, and disseminated histoplasmosis. 1 Rupioid psoriasis can occur in isolation, in association with HIV, and triggered by medications, including lithium, hydroxychloroquine, and β-blockers.…”

“…1 Rupioid psoriasis can occur in isolation, in association with HIV, and triggered by medications, including lithium, hydroxychloroquine, and β-blockers. 2 It is typically considered resistant to topical treatment. Treatment successes with systemic agents, including acitretin, cyclosporine, methotrexate, adalimumab, and ustekinumab, have all been reported.…”

“…Treatment successes with systemic agents, including acitretin, cyclosporine, methotrexate, adalimumab, and ustekinumab, have all been reported. 1,2 Other variants of hyperkeratotic psoriasis include ostraceous and elephantine forms. Rupioid and ostraceous psoriasis were initially grouped together as psoriasis exuditiva by Grzybowski, 3 in keeping with the current hypothesis that the crust is the result of voluminous serosanguineous exudate that hardens in combination with increased keratinocyte proliferation and inflammation.…”

“…The etymology of the word rupioid is derived from rhupos , Greek for filth, to describe a dirty, crusted appearance . Contemporary analogies compare the concentric cone-like scale of rupioid psoriasis with the shells of limpets . Differential diagnoses that may manifest with skin lesions of similar morphology include secondary syphilis, hyperkeratotic scabies, HIV, reactive arthritis, and disseminated histoplasmosis …”

“…Rupioid psoriasis can occur in isolation, in association with HIV, and triggered by medications, including lithium, hydroxychloroquine, and β-blockers . It is typically considered resistant to topical treatment.…”