Rupioid histoplasmosis: first case reported in an AIDS patient in Argentina

Abstract

SUMMARYDisseminated histoplasmosis is a relatively common AIDS-defining illness, occurring in almost 4% of patients living in endemic areas and it may be the first clinical expression of the HIV infection. A broad spectrum of clinical skin lesions associated with Histoplasma capsulatum infection have been described in AIDS patients, such as erythematous macules, papules, nodules, and pustules. Herpetic, acneiform, erythema multiforme-like, molluscum contagiosum-like, vasculitic, and exfoliative forms have also been reported. To our knowledge, this is the first case of disseminated histoplasmosis in an AIDS patient presented as a rupioid eruption.

Sífilis maligna en un paciente con infección por VIH: Presentación de un caso y revisión de la literatura

“…Se caracteriza por manifestaciones clínicas inespecíficas y lesiones cutáneas extensas, polimorfas, destructivas y ulcerativas, algunas con características rupioides, que pueden comprometer la vida del paciente. Las lesiones papulosas, nodulares y ulcerativas pueden estar cubiertas por costras y evolucionan en forma lenta hacia la cicatrización 1,2 . La incidencia global de sífilis secundaria maligna es baja; Shulkin y cols.…”

Correlation of CD4 counts with clinical and histopathological findings in disseminated histoplasmosis: a 10‐year retrospective study

“…Two previous studies stated that lesions were predominantly located on the face. 11,13 Another study which showed two patients with CD4 count 10 and 30 cells/mm 3 , respectively, had the same lesion distributions. In other studies, arms were also a common predilection site besides the face and upper chest.…”

“…,13 Another study which showed two patients with CD4 count 10 and 30 cells/mm 3 , respectively, had the same lesion distributions. In…”

Rupioid Psoriasis and Psoriatic Arthritis in a Patient With Skin of Color

“…3,4 Rupioid lesions also have been observed in an array of other diseases, such as secondary syphilis, crusted scabies, disseminated histoplasmosis, HIV, reactive arthritis, and aminoaciduria. [7][8][9][10][11] Diagnosis of rupioid psoriasis can be confirmed with a skin biopsy, which demonstrates characteristic histopathologic findings of psoriasis. 3 Laboratory analysis should be performed to rule out other causes of rupioid lesions, and PsA should be differentiated from rheumatoid arthritis if arthropathy is present.…”