Rubella vaccination strategy

Hinman, Alan R.

doi:10.2223/jped.1700

Cited by 3 publications

(4 citation statements)

References 6 publications

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“…' Elimination of rubella and CRS can be achieved by universal immunization of infants and seronegative women of childbearing age [12].…”

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confidence: 99%

“…Important recommendations of the WHO for CRS prevention are: Prevention of CRS can only be achieved by immunization of adolescent girls and/or women of childbearing age.Elimination of rubella and CRS can be achieved by universal immunization of infants and seronegative women of childbearing age [12]. In countries like India, where vaccine coverage may be sub-optimal, immunization of adolescent girls (and boys) and adult women may be effective for prevention of CRS.…”

mentioning

confidence: 99%

“…In countries like India, where vaccine coverage may be sub-optimal, immunization of adolescent girls (and boys) and adult women may be effective for prevention of CRS. Unlike childhood vaccination, adolescent and adult immunization has been proved to be better at reducing the number of women of childbearing age at risk of acquiring rubella infection [12, 13]. Such a shift in strategy can only be done with an overview of the susceptibility profile of the target population, the acceptability of the shift in society and the economic feasibility of such a large-scale operation.…”

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confidence: 99%

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Congenital rubella syndrome and rubella in Vellore, South India

et al. 2010

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Rubella, a mild, vaccine-preventable disease, can manifest as congenital rubella syndrome (CRS), a devastating disease of the fetus. To emphasize the inadequacy of the existing rubella vaccination programme in India, we evaluated epidemiological evidence of rubella virus activity with data available from a tertiary-care centre. The proportion of suspected CRS cases that were laboratory confirmed increased from 4% in 2000 to 11% in 2008. During the same period, 329 clinically suspected postnatal rubella cases were tested of which 65 (20%) were laboratory confirmed. Of women (n=770) of childbearing age, 12·5% were susceptible to rubella.

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“…' Elimination of rubella and CRS can be achieved by universal immunization of infants and seronegative women of childbearing age [12].…”

mentioning

confidence: 99%

mentioning

confidence: 99%

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confidence: 99%

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Congenital rubella syndrome and rubella in Vellore, South India

et al. 2010

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“…The current live attenuated vaccine is Rubella vaccine RA 27/3 (human diploid fibroblast) strain which used in combined with mumps and measles vaccine (MMR) and effectively reduce disease incidence [20][21][22][23]. However, the vaccine has some side effects such as joint symptoms that may occur in up to 60% of post pubertal female but does not cause chronic joint disease, also lymphadenopathy, rash and allergy [24][25][26].…”

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confidence: 99%

Prediction of Multiple Peptide Based Vaccine from E1, E2 and Capsid Proteins of Rubella Virus: An In-Silico Approach

Elgenaid¹,

Al-Hajj²,

Ibrahim³

et al. 2018

Immunome Res

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Rubella is a single strand RNA virus in structure that belongs to Togaviridae family. It causes rubella by respiratory droplet transmission and congenital rubella syndrome if infection to the mother occurs during pregnancy. The current life attenuated vaccine is given as part of MMR vaccine. It has many side effects and contraindicated in pregnancy and immunosuppressed persons. The aim of this study is to determine antigenic peptides from E1, E2, and Capsid proteins that can be used for multiple peptide vaccine design using In-Silico study. A total of 189 sequences of three proteins were obtained from NCBI and subjected to multiple sequence alignments using CLUSTALW tool to determine conserved regions.

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Seropositivity rates for toxoplasmosis, rubella, syphilis, cytomegalovirus, hepatitis and HIV among pregnant women receiving care at a Public Health Service, São Paulo State, Brazil

Gonçalves

Mattos

Spegiorin³

et al. 2010

The Brazilian Journal of Infectious Diseases

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Infectious and parasitic diseases affecting women during their reproductive age may result in vertical transmission. The aim of this study was to determine the seroprevalence for TORSCH among pregnant women receiving care at a university hospital. Records of 574 pregnant women who received medical attention from January 2006 to December 2007 were assessed. The mean age was 27.2 ± 6.5 years ranging from 13 to 44. The results of the immunodiagnostic tests were: 62.0% (345/556) for IgG and 3.4% (19/556) for IgM anti-T. gondii; 93.1% (433/465) for IgG and 0.6% (3/465) for IgM anti-rubella; 0.9% (5/561) for VDRL; 1.8% (10/554) for HBsAg; 0.7% (4/545) for anti-HCV and 2.1% (11/531) for HIV. In conclusion, the results of immunodiagnostic tests for the TORSCH panel among pregnant women attending a perinatal service of a university hospital are in agreement with those reported by previous studies and by governmental sources.

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Rubella vaccination strategy

Cited by 3 publications

References 6 publications

Congenital rubella syndrome and rubella in Vellore, South India

Congenital rubella syndrome and rubella in Vellore, South India

Prediction of Multiple Peptide Based Vaccine from E1, E2 and Capsid Proteins of Rubella Virus: An In-Silico Approach

Seropositivity rates for toxoplasmosis, rubella, syphilis, cytomegalovirus, hepatitis and HIV among pregnant women receiving care at a Public Health Service, São Paulo State, Brazil

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